H4128
11β-Hydroxytestosterone
crystalline
别名:
11β,17β-Dihydroxyandrost-4-en-3-one, 4-Androstene-11β,17β-diol-3-one
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关于此项目
经验公式（希尔记法）:
C19H28O3
化学文摘社编号:
分子量:
304.42
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
SMILES string
CC12CC(O)C3C(CCC4=CC(=O)CCC34C)C1CCC2O
form
crystalline
drug control
USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
color
light yellow
Biochem/physiol Actions
Structure-activity relationships of 11-substituted testosterone derivatives as progesterone agonists, and their effect on growth and differentiation of human decidual cells.
signalword
Danger
hcodes
Hazard Classifications
Carc. 2 - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
涉药品监管产品
此项目有
R Schulz
General and comparative endocrinology, 64(2), 312-319 (1986-11-01)
Male rainbow trout show high plasma androgen levels beginning with the period of full spermatogenesis until the end of spermiation. The difficulties in explaining the steroid levels in regard to the concomitant changes of the plasma GTH concentrations prompted investigations
F Ollevier et al.
General and comparative endocrinology, 61(2), 214-228 (1986-02-01)
The O-pentafluorobenzyloxime (OPFB)-heptafluorobutyrylester (HFB) derivatives of hemolymph steroid extracts from both male and female Astacus leptodactylus were subjected to negative ion chemical ionization and capillary gas chromatography-mass spectrometry (NCI/GC-MS). Five nonecdysteroid steroids, namely pregnenolone, 17 alpha-hydroxypregnenolone, testosterone, cholesterol, and 6
P M Rosenblum et al.
Comparative biochemistry and physiology. B, Comparative biochemistry, 82(4), 659-665 (1985-01-01)
Highly specific antisera for 11-keto- and 11 beta-hydroxytestosterone have been raised in sheep. Assay systems for the simultaneous measurement of 11-ketotestosterone, 11 beta-hydroxytestosterone, testosterone, progesterone and estradiol-17 beta were validated for Ictalurus nebulosus plasma and Carassius auratus serum. In males
S T Lee et al.
General and comparative endocrinology, 99(1), 41-49 (1995-07-01)
The steroidogenic potential of gonadal tissues of the protogynous grouper (Epinephelus tauvina) was examined before and after sex inversion with 17 alpha-methyltestosterone. Incubations of gonadal tissues of the fish with [3H]testosterone resulted in the biosynthesis of 5 beta-androstane-3 beta, 17
R Schlaghecke et al.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 24(8), 577-581 (1986-08-01)
A radioimmunoassay (RIA) is described for the measurement of 11 beta,17 beta-dihydroxy-4-androsten-3-one (11 beta-hydroxytestosterone) in human plasma. The reliability criteria of the new RIA were similar to those of other steroid hormone radioimmunoassays. The mean plasma 11 beta,17 beta-dihydroxy-4-androsten-3-one level
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