H3878
猪去氧胆酸
≥98%, Bile acid
别名:
3α,6α-二羟基-5β-胆烷酸
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关于此项目
经验公式（希尔记法）:
C24H40O4
化学文摘社编号:
分子量:
392.57
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
201-483-2
MDL number:
Assay:
≥98%
Quality level:
产品名称
猪去氧胆酸, ≥98%
Quality Level
assay
≥98%
mp
200-201 °C (lit.)
SMILES string
C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](O)[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI
1S/C24H40O4/c1-14(4-7-22(27)28)17-5-6-18-16-13-21(26)20-12-15(25)8-10-24(20,3)19(16)9-11-23(17,18)2/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16+,17-,18+,19+,20+,21+,23-,24-/m1/s1
InChI key
DGABKXLVXPYZII-SIBKNCMHSA-N
Gene Information
human ... NR1H2(7376), NR1H3(10062)
General description
异去氧胆酸是天然存在的次级胆汁酸。它通过小肠中的肠道菌群产生。在大鼠中，异去氧胆酸在胆汁的肠肝循环过程中由鹅去氧胆酸获得。
Application
异去氧胆酸已被用于：
- 作为液相色谱-质谱（LC-MS）联用法分析大鼠细胞中血清胆汁酸的标准品。
- 作为生长培养基的成分用于研究其作为抗衰老小分子对pex5Δ (Δ) 菌株时序寿命 (CLS) 的影响。
- 作为分析小鼠细胞中胆汁酸组成和总胆汁酸的成分。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Activation of bile acid signaling improves metabolic phenotypes in high-fat diet-induced obese mice.
Joseph F Pierre et al.
American journal of physiology. Gastrointestinal and liver physiology, 311(2), G286-G304 (2016-06-25)
The metabolic benefits induced by gastric bypass, currently the most effective treatment for morbid obesity, are associated with bile acid (BA) delivery to the distal intestine. However, mechanistic insights into BA signaling in the mediation of metabolic benefits remain an
Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes
Goldberg A A, et al.
Aging (Albany. NY.), 2(7), 393-393 (2010)
Activation of bile acid signaling improves metabolic phenotypes in high-fat diet-induced obese mice
Pierre J F, et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology, 311(2), G286-G304 (2016)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| H3878-5G | 04061832856612 |