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Merck
CN

H3661

4′-羟基双氯芬酸

≥98% (HPLC)

别名:

2-((2,6-二氯-4-羟基苯基)氨基)苯乙酸, 4′-羟基双氯灭痛

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关于此项目

经验公式(希尔记法):
C14H11Cl2NO3
化学文摘社编号:
分子量:
312.15
UNSPSC Code:
12161501
NACRES:
NA.47
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4198042
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InChI key

KGVXVPRLBMWZLG-UHFFFAOYSA-N

SMILES string

OC(=O)Cc1ccccc1Nc2c(Cl)cc(O)cc2Cl

InChI

1S/C14H11Cl2NO3/c15-10-6-9(18)7-11(16)14(10)17-12-4-2-1-3-8(12)5-13(19)20/h1-4,6-7,17-18H,5H2,(H,19,20)

assay

≥98% (HPLC)

packaging

vial of 5 mg

storage temp.

−20°C

Quality Level

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General description

4′-羟基双氯芬酸是一种重要的醋氯芬酸代谢物,主要存在于大鼠中。它是尿液中的重要氧化代谢物。
双氯芬酸的 CYP2C9 代谢物。

Application

4′-羟基双氯芬酸已被用于考察龙胆苦甙 (GE) 对人细胞色素P450酶的体外作用。它还被用作酶标记物,用于研究其在不同体外肝脏模型中的代谢活性。

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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