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Merck
CN

H3536

Sigma-Aldrich

结合柱蛋白 来源于混合人类血浆

≥95% (SDS-PAGE), lyophilized powder

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别名:
Haptoglobin from human plasma
CAS号:
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.61

生物来源

human plasma (pooled)

质量水平

检测方案

≥95% (SDS-PAGE)

形式

lyophilized powder

技术

activity assay: suitable

溶解性

H2O: soluble 10 mg/mL

UniProt登记号

储存温度

−20°C

基因信息

human ... HP(3240)

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一般描述

触珠蛋白是一种在正常血浆中发现的 α 2 -球蛋白,浓度为 82-236 mg/dL,占血浆总蛋白的 0.4-2.6%。这种急性期血浆蛋白的单体形式由四条多肽链组成:两条 α链和两个 β链条。
触珠蛋白是一种急性期蛋白,可清除释放到循环中的血红蛋白。结合珠蛋白是与血红蛋白亲和力最高的血浆蛋白,主要在肝脏中表达。

应用

结合珠蛋白用于研究诱导精子顶体反应。暴露于低温会增加它们与无透明带仓鼠卵母细胞的融合率。

生化/生理作用

通过与血浆血红蛋白结合(来自溶血)发挥作用。该复合物通过与巨噬细胞上的 CD163 受体结合,从循环中清除,以挽救铁并防止氧化损伤。

其他说明

作为 3 种主要表型出现:1-1 型、2-1 型、2-2 型。

免责声明

仅供研究使用。在法国,在用于科研目的时(包括进口和出口活动(《公共健康法》第L 1211-1条,第2节))该产品为管制品。购买者(即最终用户)需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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