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Merck
CN
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安全信息

H2667

Sigma-Aldrich

Histone H4 human

别名:

Histone, Human

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About This Item

UNSPSC代码:
12352202
NACRES:
NA.25

生物来源

human

质量水平

重组

expressed in E. coli

表单

liquid

浓度

1 mg/mL

UniProt登记号

运输

wet ice

储存温度

−20°C

基因信息

human ... H4C1(121504)

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一般描述

Histones are highly basic chromatin proteins. They tightly pack and organize eukaryotic DNA into nucleosomes. Nucleosomes consist of a histone octamer made of a tetramer of histones H3 and H4 with two dimers of histones H2A and H2B, wherein the 147 DNA base pairs are wrapped around this histone complex.

应用

Histone H4 human has been used in far-western blot analysis for protein identification. It has also been used in the preparation of standard protein solution for protein digestion.

生化/生理作用

Histones regulate transcription, DNA replication, DNA repair, and recombination.

其他说明

Supplied as 1 mg/mL in 20 mM NaPO4, pH 7.0, 0.3 M NaCl, 1 mM EDTA

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Shi Zheng et al.
Proteomics, 16(7), 1059-1068 (2016-02-04)
Concentrated formic acid is among the most effective solvents for protein solubilization. Unfortunately, this acid also presents a risk of inducing chemical modifications thereby limiting its use in proteomics. Previous reports have supported the esterification of serine and threonine residues
Khoa N Pham et al.
The journal of physical chemistry. B, 125(19), 4977-4986 (2021-05-12)
Histones are highly basic chromatin proteins that tightly package and order eukaryotic DNA into nucleosomes. While the atomic structure of the nucleosomes has been determined, the three-dimensional structure of DNA-free histones remains unresolved. Here, we combine tandem nonlinear and linear
Apurva Bhardwaj et al.
International journal of molecular sciences, 22(1) (2021-01-07)
Insulin-like growth factor (IGF) binding protein-3 (IGFBP-3) is an essential protein that regulates cellular processes such as cell proliferation, apoptosis, and differentiation. It is known to bind with several proteins to carry out various cellular functions. In this study, we

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