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H1792

Sigma-Aldrich

贯叶金丝桃素 二环己基铵盐

别名:

Hyp-DCHA, 贯叶金丝桃素-DCHA

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1 MG
¥3,983.71

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1 MG
¥3,983.71

About This Item

经验公式（希尔记法）:
C35H52O4·C12H23N
CAS号:
238074-03-8
分子量:
718.10
MDL编号:
MFCD04000098
UNSPSC代码:
12352200
PubChem化学物质编号:
329815179
NACRES:
NA.25

¥3,983.71

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方案

≥98% (HPLC)

表单

powder

储存条件

protect from light

颜色

white to off-white

溶解性

DMSO: ≥10 mg/mL

储存温度

−20°C

SMILES字符串

C1CCC(CC1)NC2CCCCC2.CC(C)C(=O)[C@@]34C(O)=C(C\C=C(\C)C)C(=O)[C@@](C\C=C(\C)C)(C[C@H](C\C=C(/C)C)[C@@]3(C)CC\C=C(\C)C)C4=O

InChI

1S/C35H52O4.C12H23N/c1-22(2)13-12-19-33(11)27(16-14-23(3)4)21-34(20-18-25(7)8)30(37)28(17-15-24(5)6)31(38)35(33,32(34)39)29(36)26(9)10;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h13-15,18,26-27,38H,12,16-17,19-21H2,1-11H3;11-13H,1-10H2/t27-,33+,34+,35-;/m0./s1

InChI key

ZUYCAROZOLUHJY-DNSWOBEMSA-N

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此商品
C990173332642891
贯叶金丝桃素 二环己基铵盐

H1792

贯叶金丝桃素 二环己基铵盐

N6-Cyclohexyladenosine

C9901

N6-Cyclohexyladenosine

顺式-4,7,10,13,16,19-二十二碳六烯酸-21,21,22,22,22-d5 ≥98 atom % D, ≥98% (CP)

733326

顺式-4,7,10,13,16,19-二十二碳六烯酸-21,21,22,22,22-d5

贯叶金丝桃素 二环己基铵盐 analytical standard

42891

贯叶金丝桃素 二环己基铵盐

assay

≥98% (HPLC)

assay

-

assay

≥98% (CP)

assay

≥98.0% (HPLC)

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

-

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

solubility

DMSO: ≥10 mg/mL

solubility

-

solubility

-

solubility

-

storage condition

protect from light

storage condition

-

storage condition

-

storage condition

-

生化/生理作用

贯叶金丝桃素的稳定盐。
贯叶金丝桃素的稳定盐。贯叶金丝桃素被认为是负责圣约翰草′提取物的抗抑郁和抗焦虑特性的主要活性成分。它通过激活瞬时受体电位离子通道TRPC6充当单胺（包括5-羟色胺，去甲肾上腺素，多巴胺以及GABA和谷氨酸）的再摄取抑制剂。激活TRPC6可诱导钠和钙进入细胞，从而抑制单胺再摄取。它也是孕烷X受体（PXR）的激活剂，它是CYP3A4转录的关键调节剂，CYP3A4是细胞色素（CYP）P450酶系统的成员。最近的研究发现了其他神经系统作用，对炎症的作用以及抗菌、抗肿瘤和抗血管生成作用。
贯叶金丝桃素被认为是负责圣约翰草′提取物的抗抑郁和抗焦虑特性的主要活性成分。
贯叶金丝桃素被认为是负责圣约翰草′提取物的抗抑郁和抗焦虑特性的主要活性成分。它通过激活瞬时受体电位离子通道TRPC6充当单胺（包括5-羟色胺，去甲肾上腺素，多巴胺以及GABA和谷氨酸）的再摄取抑制剂。它也是孕烷X受体（PXR）的激活剂，它是CYP3A4转录的关键调节剂，CYP3A4是细胞色素（CYP）P450酶系统的成员。最近的研究发现它对阿尔茨海默氏′病（AD）神经病理学具有神经保护作用，包括在体外分解淀粉样蛋白β聚集体和改善体内空间记忆的能力。[1]

警示用语：

Danger

危险声明

H302,H314,H400

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1B

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    0000354442
    0000349355
    0000354442
    0000349355
    0000129551

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