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生物来源
human
质量水平
重组
expressed in Baculovirus infected High-5 cells
检测方案
>95% (SDS-PAGE)
形式
lyophilized powder
效能
1.0-20.0 ng/mL
质量
endotoxin tested
分子量
~80 kDa
包装
pkg of 5x5 μg
pkg of 5 μg
储存条件
avoid repeated freeze/thaw cycles
技术
cell culture | mammalian: suitable
杂质
<1.0 EU/μg
UniProt登记号
储存温度
−20°C
基因信息
human ... HGF(3082)
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生化/生理作用
肝细胞生长因子（HGF）是肝细胞和多种细胞类型（包括内皮和上皮细胞、黑素细胞和角质形成细胞）的有效促分裂原。它还可介导上皮形态发生。HGF是由met原癌基因编码的酪氨酸激酶受体的配体。
其他说明
NSO表达的重组HGF含有大于95％的异二聚体HGF。昆虫细胞系表达的重组HGF是单链HGF（主要）和一些异二聚体HGF的混合物。单链HGF和异二聚体HGF在 体外 分析中具有相同的活性。
外形
从经0.2μm过滤的含有20 mM NaH2PO4 (pH 7.0)和500 mM NaCl,并且每1μg HGF中含50μg BSA的溶液冻干得到
制备说明
在含有至少0.1％人或牛血清白蛋白的无菌PBS中以50μg/mL的浓度进行复溶。复溶后，该溶液可以在2-8°C下最多保存一个月，或在-20°C到-70°C下最多保存三个月。请使用手动除霜冷冻柜，并避免反复冻融。
分析说明
生物学活性通过其诱导Saos-2人骨肉瘤细胞分泌IL-11的能力进行测定。
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
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Hepatocyte growth factor (HGF) is a potent mitogen for hepatocytes and a variety of other cells, including endothelial and epithelial cells, melanocytes, and keratinocytes.
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