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Merck
CN

H1291

Sigma-Aldrich

Anti-HOXA1 antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

别名:

Anti-HXA1, Anti-Homeobox A1, Anti-Hox-1.6, Anti-Hox-1F

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About This Item

UNSPSC代码:
12352203

生物来源

rabbit

偶联物

unconjugated

抗体形式

IgG fraction of antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

antigen ~43 kDa

种属反应性

human

技术

western blot: 1:500-1:1,000 using lysate of HEK-293T cells over expressing human HOXA1

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... HOXA1(3198)

一般描述

The HOXA1 gene is a member of the homeobox (HOX) gene family and is mapped on the human chromosome at 7p15.2.

特异性

Anti-HOXA1 specifically recognizes human HOXA1 (also known as Hox-1F, HXA1).

应用

Anti-HOXA1 antibody produced in rabbit may be used in immunoblotting.

生化/生理作用

Homeobox A1 (HOXA1) protein is involved in hindbrain segmentation and patterning. Misregulation of the HOXA1 gene is associated with breast cancer. HOXA1 gene disruption results in abnormal ossification of the skull, hindbrain, and inner ear deficiencies, and neonatal death.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

储存及稳定性

Store at –20 °C. For continuous use, the product may be stored at 2–8 °C for up to one month. For extended storage, freeze in working aliquots at –20 °C. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Liliana A Muñoz-Pedroza et al.
Acta otorrinolaringologica espanola, 64(5), 359-362 (2013-07-31)
Facio-Auriculo-Vertebral (FAV) spectrum, also known as Goldenhar syndrome or first and second branchial arch syndrome, is a complex of mainly craniofacial and vertebral anomalies. Microtia is a principal malformation in this complex; it can be unilateral or bilateral. We performed
Barbara Lambert et al.
BMC developmental biology, 12, 29-29 (2012-10-24)
Hox proteins are transcription factors involved in crucial processes during animal development. Their mode of action remains scantily documented. While other families of transcription factors, like Smad or Stat, are known cell signaling transducers, such a function has never been

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