推荐产品
方案
≥98% (HPLC)
包含
ascorbic acid as stabilizer
mp
216-220 °C (lit.)
储存温度
−20°C
SMILES字符串
Br.NCCc1cc(O)c(O)cc1O
InChI
1S/C8H11NO3.BrH/c9-2-1-5-3-7(11)8(12)4-6(5)10;/h3-4,10-12H,1-2,9H2;1H
InChI key
MLACDGUOKDOLGC-UHFFFAOYSA-N
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一般描述
方便、稳定地制备多巴胺能神经毒素，6-羟基多巴胺。
溶液应新鲜制备，并且应避光。
重悬
每 5mg 小瓶加入 2mL 缓冲液，得到含有 10mM 6-羟基多巴胺和 0.01％（w/v）抗坏血酸的溶液。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
William Menegas et al.
Nature neuroscience, 21(10), 1421-1430 (2018-09-05)
Midbrain dopamine neurons are well known for their role in reward-based reinforcement learning. We found that the activity of dopamine axons in the posterior tail of the striatum (TS) scaled with the novelty and intensity of external stimuli, but did
Woori Kim et al.
Neurobiology of aging, 35(7), 1712-1721 (2014-02-25)
Dopamine (DA) neurons in sporadic Parkinson's disease (PD) display dysregulated gene expression networks and signaling pathways that are implicated in PD pathogenesis. Micro (mi)RNAs are regulators of gene expression, which could be involved in neurodegenerative diseases. We determined the miRNA
Julio C Tobón-Velasco et al.
Toxicology, 304, 109-119 (2013-01-01)
6-Hydroxydopamine (6-OHDA) is a neurotoxin that generates an experimental model of Parkinson's disease in rodents and is commonly employed to induce a lesion in dopaminergic pathways. The characterization of those molecular mechanisms linked to 6-OHDA-induced early toxicity is needed to
Ana Freitas et al.
Antioxidants (Basel, Switzerland), 10(7) (2021-08-07)
Parkinson's disease's etiology is unknown, although evidence suggests the involvement of oxidative modifications of intracellular components in disease pathobiology. Despite the known involvement of the extracellular matrix in physiology and disease, the influence of oxidative stress on the matrix has
C C Real et al.
Neuroscience, 237, 118-129 (2013-02-12)
Physical exercise is known to produce beneficial effects to the nervous system. In most cases, brain-derived neurotrophic factor (BDNF) is involved in such effects. However, little is known on the role of BDNF in exercise-related effects on Parkinson's disease (PD).
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