推荐产品
生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen ~50 kDa
种属反应性
human
浓度
~1.0 mg/mL
技术
western blot: 1-2 μg/mL using lysates of HEK-293T cells over expressing human HOXA10
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... HOXA10(3206)
一般描述
The homeobox A10 (HOXA10) protein is localized in the adult human endometrium. The HOXA10 gene is mapped on the human chromosome at 7p15.2.
特异性
Anti-HOXA10 (N-terminal) recognizes human HOXA10 (also known as Hox-1H and HOX-1).
应用
Anti-HOXA10 (N-terminal) antibody produced in rabbit has been used in immunoblotting.
生化/生理作用
Homeobox A10 (HOXA10) protein is critical for the normal development of the erythroid and megakaryocytic lineages. The expression of the HOXA10 gene was found to be altered in endometriosis. HOXA10 protein plays a role in mediating endometrial development during the menstrual cycle. This protein is also involved in preparing the endometrium for implantation in humans.
外形
0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。
储存及稳定性
For continuous use, store at 2–8 °C for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
从最新的版本中选择一种:
Molecular human reproduction, 13(5), 323-332 (2007-03-14)
Endometriosis is a poorly understood gynaecologic disorder that is associated with infertility. In this study, we examined the expression of HOXA10 in the eutopic endometrium of baboons with induced endometriosis. A decrease in HOXA10 mRNA was observed after 3, 6
The Journal of clinical investigation, 101(7), 1379-1384 (1998-04-29)
Hox genes are well-known transcriptional regulators that play an essential role in directing embryonic development. Mice that are homozygous for a targeted disruption of the Hoxa10 gene exhibit uterine factor infertility. We have recently demonstrated that HOXA10 is expressed in
Journal of assisted reproduction and genetics, 27(12), 701-710 (2010-09-08)
endometriosis and its associated infertility have been the object of continuous research for over a century. To understand the molecular mechanisms underlying the disease, it has become necessary to determine the aspects of its etiology that are not explained by
Oncotarget, 6(33), 34745-34757 (2015-10-03)
The homeobox A (HOXA) region of protein-coding genes impacts female reproductive system embryogenesis and ovarian carcinogenesis. The 5-prime end of HOXA includes three long non-coding RNAs (lncRNAs) (HOXA10-AS, HOXA11-AS, and HOTTIP) that are underexplored in epithelial ovarian cancer (EOC). We
The Journal of clinical investigation, 126(3), 997-1011 (2016-02-16)
Self-renewal is a hallmark of both hematopoietic stem cells (HSCs) and leukemia stem cells (LSCs); therefore, the identification of mechanisms that are required for LSC, but not HSC, function could provide therapeutic opportunities that are more effective and less toxic
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