跳转至内容
Merck
CN

H0878

肝素 锂盐 来源于猪肠粘膜

≥150 USP units/mg

别名:

Lithium acid heparin, Lithium heparinate

登录 查看组织和合同定价。

选择尺寸

关于此项目

化学文摘社编号:
9045-22-1
UNSPSC Code:
12352201
NACRES:
NA.25
MDL number:
MFCD00131308

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

肝素 锂盐 来源于猪肠粘膜, ≥150 USP units/mg

SMILES string

[S](=O)(=O)(NC1C(OC(C(C1O)OC2OC(C(C(C2O[S](=O)(=O)O)O)OC)C(=O)O)CO[S](=O)(=O)O)OC)O

InChI

1S/C14H25NO20S3/c1-29-9-7(17)10(35-38(26,27)28)14(34-11(9)12(18)19)33-8-4(3-31-37(23,24)25)32-13(30-2)5(6(8)16)15-36(20,21)22/h4-11,13-17H,3H2,1-2H3,(H,18,19)(H,20,21,22)(H,23,24,25)(H,26,27,28)

InChI key

HXSDFQWQRCUQHF-UHFFFAOYSA-N

biological source

Porcine intestinal mucosa

form

powder

specific activity

≥150 USP units/mg

color

off-white

solubility

water: 40 mg/mL, clear, colorless to faint yellow or tan

cation traces

Li: 3-4%

application(s)

diagnostic assay manufacturing
life science and biopharma
plasma purification
sample preparation

storage temp.

room temp

Quality Level

200

正在寻找类似产品? 访问 产品对比指南

相关类别

Other Notes

For additional information on our range of Biochemicals, please complete this form.
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Application

Heparin lithium was used:
  • To validate photometric measurements in cell surface charge determination
  • As an anti-coagulant for laboratory studies
  • To study hypothermal stress on lactate metabolism
  • To study the effects of anticoagulants in direct membrane feeding assays
  • For 2D and 3D vitro cell culture in glioblastoma cell models
  • To prevent clot formation and tissue damage during mechanical probing of cardiac pacemaker cell embryonic patterning, a study that contributes to the broader area of cardiac tissue mechanics research and developmental biology

Features and Benefits

  • Heparin with specific activity of ≥150 USP units/mg
  • Versatile and adaptable for a wide variety of laboratory and research applications

General description

Heparin lithium is a highly sulfated polysaccharide that belongs to the family of glycosaminoglycans with remarkable significance in the areas of cell culture, cancer biology, biochemical, and drug discovery research. Due to its interactions with proteins and cells, it is used to study molecular and cellular processes, tumor modeling, investigate binding interactions, and as a cell culture supplement, to maintain cell viability.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000500343
0000500343
0000493712
0000493712
0000484309

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the potency of Product H0878, Heparin lithium salt from porcine intestinal mucosa?

    The specification for potency is ? 150 USP units/mg.  The lot specific potency can be found on the Certificate of Analysis, which can be accessed on the Product Detail page.

  4. How much heparin is needed to prevent coagulation in whole blood?

    Typically, between 20 and 50 units per mL of whole blood are needed.

  5. How can Product H0878, Heparin lithium salt from porcine intestinal mucosa be reconstituted?

    The solubility of heparin is 40 mg/mL in water.

  6. What is the solution stability of Product H0878, Heparin lithium salt from porcine intestinal mucosa?

    Heparin is a polysaccharide, which has excellent aqueous solution stability (up to 2 years at 2-8 °C) provided the solutions have been sterilized by filtration through a 0.2 μm membrane.  More solution stability information can be on the product information sheet (under Documents, above).

  7. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  8. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  9. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

The effect of anticoagulants in blood collection tubes on Plasmodium falciparum transmission in direct membrane feeding assays
Wouter G et al.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 116, 187- 189 (2022)
Determination of cell surface charge by photometric titration
Thethi K et al
Journal of Biochemical and Biophysical Methods, 34, 137-145 (1997)
Chia-Hao Chang et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 248, 110744-110744 (2020-06-23)
The milkfish Chanos chanos, an economically important cultured marine species in Southeast Asia, exhibits stenothermal and euryhaline characteristics and huge mortality usually occurs during extreme cold weather in winter. Under conditions beyond optimal temperatures, ectothermic species experience an increase in
R B Shartau et al.
The Journal of experimental biology, 223(Pt 7) (2020-03-05)
Acute (<96 h) exposure to elevated environmental CO2 (hypercarbia) induces a pH disturbance in fishes that is often compensated by concurrent recovery of intracellular and extracellular pH (pHi and pHe, respectively; coupled pH regulation). However, coupled pH regulation may be limited
Beatriz Giesen et al.
Pharmaceutics, 13(2) (2021-03-07)
Gold nanoparticles (Au NPs) are studied as delivery systems to enhance the effect of the glutaminase1 inhibitor CB839, a promising drug candidate already in clinical trials for tumor treatments. Au NPs were synthesized using a bottom-up approach and covered with
查看所有相关文献

商品

Glycosaminoglycan Sulfation and Signaling

Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.

Pharmaceutical Research Applications of Carbohydrates and Polysaccharides

Discover the role of carbohydrates in drug delivery, from solubility and stability improvement to advanced controlled-release systems.

Carbohydrates as Versatile Enablers of Advanced Drug Delivery Systems

Explore how carbohydrates function as excipients and carriers in drug delivery, with insights into mechanisms, case studies, and future trends.

相关内容

Product Information Sheet - H0878

Product Information Sheet

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持