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生物来源
chicken
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
种属反应性
human
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... ST8SIA1(6489)
一般描述
The previously assigned protein identifier Q6PZN5 has been merged into Q92185. Full details can be found on the UniProt database.
免疫原
Immunogen Sequence: GI # 4506953, sequence 4-18
Synthetic peptide sequence of ST8 α-N-acetyl-neuraminide α-2,8-sialyltransferase 1.
应用
Anti-ST8SIA1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
α-N-acetylneuraminide α-2,8-sialyltransferase is an enzyme encoded by the ST8SIA1 gene in humans. It acts as an oligosialyltransferase in a cellular context. ST8SIA1 gene encodes a ganglioside synthase and is susceptibile to diseases. The gene is found to be associated with Multiple sclerosis (MS).
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
Agata Steenackers et al.
Molecules (Basel, Switzerland), 17(8), 9559-9572 (2012-08-14)
Glycosphingolipids from the ganglio-series are usually classified in four series according to the presence of 0 to 3 sialic acid residues linked to lactosylceramide. The transfer of sialic acid is catalyzed in the Golgi apparatus by specific sialyltransferases that show
Sreeram V Ramagopalan et al.
Journal of neuroimmunology, 212(1-2), 142-144 (2009-05-12)
Multiple sclerosis (MS) is a complex trait with a significant genetic component. Recent work has implicated the ST8SIA1 gene, encoding a ganglioside synthase, in susceptibility to the disease, perhaps with a parent-of-origin effect. In this investigation of 1318 MS patients
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