生物来源
chicken
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
种属反应性
human
制造商/商品名称
Genway 15-288-22770
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... MAPK7(5598)
免疫原
Immunogen Sequence: GI # 20986497, sequence 341-570
Recombinant mitogen-activated protein kinase 7 isoform 1
应用
Anti-MAPK7 (ab2) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
Mitogen-activated protein kinase 7 (also known as MAP kinase 7) is an enzyme encoded by the MAPK7 gene in humans and is mapped to chromosome 17 band p11.2. It belongs to mitogen-activated protein kinase (MAPK) family and regulates a wide variety of cellular processes such as proliferation, differentiation, necrosis, apoptosis and degeneration. MAPK7 is involved in degeneration of nucleus pulposus. Expression of MAPK7 may act as a valuable indicator for predicting lung cancer risk in smokers.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
Weiguo Liang et al.
Biochemical and biophysical research communications, 449(4), 466-470 (2014-05-27)
Extracellular-signal-regulated kinase 5 (ERK5) is a member of the mitogen-activated protein kinase (MAPK) family and regulates a wide variety of cellular processes such as proliferation, differentiation, necrosis, apoptosis and degeneration. However, the expression of ERK5 and its role in degenerated
Fuman Qiu et al.
Mutagenesis, 28(5), 561-567 (2013-06-28)
Mitogen/extracellular signal-regulated kinase-5 (MEK5)/extracellular signal-regulated protein kinase-5 (ERK5) pathway plays a pro-oncogenic role in tumourigenesis by anticell apoptosis, promoting cell proliferation and differentiation in response to extracellular stimuli. As overexpressed MEK5/ERK5 is involved in the development of lung cancer, we
Assignment of big MAP kinase (PRKM7) to human chromosome 17 band p11.2 with somatic cell hybrids.
S M Purandare et al.
Cytogenetics and cell genetics, 83(3-4), 258-259 (1999-03-11)
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