推荐产品
生物来源
chicken
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
human
制造商/商品名称
Genway 15-288-21353
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... ITGAX(3687)
一般描述
ITGAX (integrin, αX), also called CD11c, belongs to the integrin superfamily of glycoproteins. It is expressed on monocytes, inflammatory macrophages, dendritic cells, and neutrophils.
应用
Anti-ITGAX antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
The expression of Integrin, αX (complement component 3 receptor 4 subunit) (ITGAX) on monocytes helps in establishing a CMML (chronic myelomonocytic leukemia) diagnosis. Polycystic ovary syndrome (PCOS) is associated with an increase in CD11c expression. Its expression is rare in mantle cell lymphoma (MCL) and may aid in differentiation of CD5+ B-cell neoplasms.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
Teresa S Kraus et al.
American journal of clinical pathology, 134(2), 271-277 (2010-07-28)
Flow cytometric immunophenotyping (FCI) aids in the differentiation of chronic lymphocytic leukemia (CLL) from mantle cell lymphoma (MCL); however, overlapping phenotypes may occur. CD11c expression has been reported in up to 90% of CLL cases but has rarely been reported
Payal Sojitra et al.
American journal of clinical pathology, 140(5), 686-692 (2013-10-15)
To examine the utility of CD11c expression on monocytes in normal controls and patients with chronic myelomonocytic leukemia (CMML) (n = 23) with flow cytometric immunophenotyping. Twenty-three CMML samples and 10 control bone marrows submitted for lymphoma staging without evidence
Zhi Hua Huang et al.
The Journal of clinical endocrinology and metabolism, 98(1), E17-E24 (2012-11-03)
Adipose tissue macrophage (ATM) infiltration is a major pathway for obesity-induced insulin resistance but has not been studied as a mechanism for insulin resistance in PCOS. We tested whether polycystic ovary syndrome (PCOS) is associated with increased ATM infiltration, especially
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