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Merck
CN

GW21213

Sigma-Aldrich

Anti-KCMF1 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

别名:

Anti-Hypothetical protein KCMF1, Anti-PCMF, Anti-Potassium channel modulatory factor

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

chicken

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

种属反应性

human

制造商/商品名称

Genway 15-288-21213

技术

western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... KCMF1(56888)

免疫原

Immunogen Sequence: GI # 10047128, sequence 280-375
Recombinant potassium channel modulatory factor

应用

Anti-KCMF1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

KCMF1 (DEBT91) is mapped to chromosome 2p11.2 in humans. It encodes a 381 amino acid molecule with high Ser and Thr composition and is highly conserved at its N-terminus across species. DEBT91 is suggested to be a coiled-coil nuclear phosphoprotein with zinc finger motifs at the N-terminal conserved region, which is rich in cysteine and histidine. It is an immediate early gene up-regulated during growth factor-induced branching tubulogenesis. DEBT91 plays an important role in gastric carcinogenesis. Its upregulation in response to bFGF in gastric cancer might be implicated in carcinogenesis through dysregulation of growth modulator.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

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分析证书(COA)

Lot/Batch Number

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Jun-Hyeog Jang
FEBS letters, 578(1-2), 21-25 (2004-12-08)
We have previously shown that fibroblast growth factor receptor 2 (FGFR2) plays an important role in gastric carcinogenesis. In this study, we have used a differential display approach to identify basic fibroblast growth factor (bFGF)-inducible genes in gastric cancer cells.
Zhixing Li et al.
Biochemical and biophysical research communications, 306(3), 623-628 (2003-06-18)
In a differential screen for genes that might be important in the regulation of epithelial morphogenesis, we identified a novel gene, Debt91 (differentially expressed in branching tubulogenesis), which is up-regulated in an in vitro model of renal tubulogenesis and branching.

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