推荐产品
生物来源
chicken
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
种属反应性
mouse, human, rat
制造商/商品名称
Genway 15-288-21143
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... JUN(3725)
免疫原
Immunogen Sequence: GI # 4758616, sequence 1-240
Recombinant V-jun avian sarcoma virus 17 oncogene homolog
应用
Anti-AP-1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
c-Jun is a protein encoded by the JUN gene in humans. c-Jun in combination with c-Fos results in the formation of the AP-1 early response transcription factor. It is crucially involved in propagation of macrophage-driven inflammatory networks. AP1 may guide for the treatment decisions for endometriosis management and may provide a mechanistic endpoint for assessing efficacy of new agents aimed at curtailing inflammatory mechanisms that drive disease progression. It may possibly be utilized for the treatment of HPV-induced cervical cancers.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
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International journal of clinical and experimental pathology, 11(8), 4221-4229 (2018-08-01)
Visible light has been previously demonstrated to induce retina damage and retinal ganglion cell (RGC) death through the mitochondrial pathway. The Fra-2 gene was detected as a transcriptional regulator, but whether it is involved in light-induced retina damage remains unclear.
Michael T Beste et al.
Science translational medicine, 6(222), 222ra16-222ra16 (2014-02-07)
Clinical management of endometriosis is limited by the complex relationship between symptom severity, heterogeneous surgical presentation, and variability in clinical outcomes. As a complement to visual classification schemes, molecular profiles of disease activity may improve risk stratification to better inform
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