生物来源
chicken
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
human
制造商/商品名称
Genway 15-288-21070
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... CXCL9(4283)
一般描述
CXCL9 (chemokine (C-X-C motif) ligand 9) is a ligand for chemokine (C-X-C motif) receptor 3 (CXCR3), which is inducible by interferon-γ. It is expressed on CD4+ Th1 cells and CD8+ cytotoxic T cells. It is also secreted by neutrophils and macrophages. It acts as a chemoattractant for activated T-lymphocytes.
应用
Anti-CXCL9 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
Chemokine (C-X-C motif) ligand 9 (CXCL9) is more abundantly expressed in tumors cells than in normal epithelium. CXCL9 is associated with tumor and aggressiveness of NPC (nasopharyngeal carcinoma) tumors and the serum level of this may be useful as a prognostic indicator. In NPC tumors, serum concentration is found to be significantly higher. CXCL9 can act as a potential therapeutic target for human CGGN (Cryoglobulinemic glomerulonephritis).
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
J Kowalewska et al.
Advances in medical sciences, 58(2), 394-400 (2013-10-03)
Cryoglobulinemic glomerulonephritis (CGGN) is a type of membranoproliferative glomerulonephritis (MPGN) that develops in patients with systemic cryoglobulinemia. To date the exact pathogenesis of CGGN remains unclear. It has been suggested that macrophages may be significant contributors to the glomerular injury
Carrie L Kitko et al.
Blood, 123(5), 786-793 (2013-12-24)
There are no validated biomarkers for chronic GVHD (cGVHD). We used a protein microarray and subsequent sequential enzyme-linked immunosorbent assay to compare 17 patients with treatment-refractory de novo-onset cGVHD and 18 time-matched control patients without acute or chronic GVHD to
Li-Jen Hsin et al.
PloS one, 8(11), e80052-e80052 (2013-11-28)
The aim of this cohort study was to examine the role of the chemokine (C-X-C motif) ligand 9 (CXCL9) on nasopharyngeal carcinoma (NPC). Sera from 205 NPC patients and 231 healthy individuals, and 86 NPC tumor samples were enrolled. CXCL9
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