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Merck
CN

GW21037

Sigma-Aldrich

Anti-CXCL10 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

别名:

Anti-Small inducible cytokine B10

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

chicken

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

种属反应性

human

制造商/商品名称

Genway 15-288-21037

技术

indirect ELISA: suitable
western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... CXCL10(3627)

免疫原

Immunogen Sequence: GI # 4504701, sequence 22-98
Recombinant small inducible cytokine B10

应用

Anti-CXCL10 antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

C-X-C motif chemokine 10 (CXCL10) is a protein encoded by the CXCL10 gene in humans. It is a potent chemoattractant for antiviral T-cells and NK-cells and is poorly associated with chronic hepatitis C virus (HCV). CXCL10 axis inhibits antiviral innate and adaptive host immunity, thereby favouring establishment of viral persistence. CXCL10 gene promoter may be partially responsible for the severity of cerebral malaria CM outcomes in males. Study shows the correlation of CXCL10 with the immunopathogenesis of vitiligo, an autoimmune disorder.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Antonio Riva et al.
Hepatology (Baltimore, Md.), 60(2), 487-496 (2014-03-29)
The pathogenesis of hepatitis C virus (HCV) infection is strongly influenced by the nature of the host's antiviral immunity. Counterintuitively, elevated serum concentrations of C-X-C chemokine 10 (CXCL10), a potent chemoattractant for antiviral T-cells and NK-cells, are associated with poor
Nana Wilson et al.
PloS one, 8(12), e81329-e81329 (2013-12-19)
The risk factors for cerebral malaria (CM) and the wide variation in clinical manifestations of malaria are poorly understood. Recent studies indicate that interferon gamma inducible chemokine, CXCL10, is a strong predictor of both human and experimental cerebral malaria. Increased
The role of the Th1 chemokine CXCL10 in vitiligo.
Alessandro Antonelli et al.
Annals of translational medicine, 3(Suppl 1), S16-S16 (2015-06-06)

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