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Merck
CN

GW21007A

Sigma-Aldrich

Anti-α-2B Adrenergic Receptor antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

别名:

Anti-α-2B Adrenergic Receptor, Anti-α-2B adrenoreceptor

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

chicken

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

种属反应性

human

制造商/商品名称

Genway 15-288-21007A

技术

western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... ADRA2B(151)

免疫原

Immunogen Sequence: GI # 4501965, sequence 200-299
Recombinant α-2B-adrenergic receptor; α-2-adrenergic receptor-like 1

应用

Anti-α-2B Adrenergic Receptor antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

The α-2B adrenergic receptor (α2B adrenoceptor) is a G-protein coupled receptor and is a subtype of the adrenergic receptor family. It is encoded by ADRA2B gene in humans. Mutation in this gene is associated with autosomal dominant cortical myoclonus and epilepsy (ADCME). ADRA2B influences norepinephrine activity. It helps in increasing emotional memory and neural activity. A genetic variation of the noradrenergic system may preserve emotional faces from stress-induced memory impairments under control conditions.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Rebecca M Todd et al.
Psychological science, 24(11), 2244-2253 (2013-09-24)
Emotionally enhanced memory and susceptibility to intrusive memories after trauma have been linked to a deletion variant (i.e., a form of a gene in which certain amino acids are missing) of ADRA2B, the gene encoding subtype B of the α2-adrenergic
Shijia Li et al.
Neurobiology of learning and memory, 103, 11-18 (2013-04-16)
Previous studies have shown that acute psychosocial stress impairs retrieval of declarative memory with emotional material being especially sensitive to this effect. A functional deletion variant of the ADRA2B gene encoding the α2B-adrenergic receptor has been shown to increase emotional
Maurizio De Fusco et al.
Annals of neurology, 75(1), 77-87 (2013-10-12)
Autosomal dominant cortical myoclonus and epilepsy (ADCME) is characterized by distal, fairly rhythmic myoclonus and epilepsy with variable severity. We have previously mapped the disease locus on chromosome 2p11.1-q12.2 by genome-wide linkage analysis. Additional pedigrees affected by similar forms of

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