推荐产品
生物来源
chicken
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
human
制造商/商品名称
Genway 15-288-20090F
技术
indirect ELISA: suitable
western blot: suitable
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... VLDLR(7436)
应用
Anti-VLDL antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
The very-low-density-lipoprotein receptor (VLDLR) is a transmembrane lipoprotein receptor and belongs to low-density-lipoprotein (LDL) receptor family. It is encoded by the VLDLR gene in humans. The LDL receptor gene family members are involved in ligand-mediated signal transduction. VLDLR is involved in the Reelin signaling pathway helping in neuronal migration in the cerebral cortex and cerebellum. It is strongly induced during adipogenesis and actively participates in adipocyte hypertrophy. VLDLR contributes to adipose tissue inflammation and mediates VLDL-induced lipid accumulation. It induces inflammation and ER stress in adipocytes and macrophages. VLDL receptor also plays a role in signaling processes.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
J Nimpf et al.
Biochimica et biophysica acta, 1529(1-3), 287-298 (2000-12-09)
The discovery of an ever growing number of low density lipoprotein (LDL) receptor gene family members has triggered research into many different directions. Here we first summarize the results of classical studies on the role of the LDL receptor in
Andrew Nguyen et al.
The Journal of biological chemistry, 289(3), 1688-1703 (2013-12-03)
Obesity is associated with adipose tissue remodeling, characterized by adipocyte hypertrophy and macrophage infiltration. Previously, we have shown that very low density lipoprotein receptor (VLDLR) is virtually absent in preadipocytes but is strongly induced during adipogenesis and actively participates in
Praseetha Kizhakkedath et al.
Biochimica et biophysica acta, 1843(12), 2871-2877 (2014-09-01)
Dysequilibrium syndrome (DES, OMIM 224050) is a genetically heterogeneous condition that combines autosomal recessive non-progressive cerebellar ataxia with mental retardation. The subclass dysequilibrium syndrome type 1 (CAMRQ1) has been attributed to mutations in the VLDLR gene encoding the very low
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