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Merck
CN

GW20080F

Sigma-Aldrich

Anti-Haptoglobin antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

别名:

Anti-MGC111141

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About This Item

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

chicken

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

种属反应性

human, rat, mouse

制造商/商品名称

Genway 15-288-20080F

技术

indirect ELISA: suitable
western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... HP(3240)

免疫原

Haptoglobin native protein.
Immunogen Sequence: GI # 4826762, sequence 1-406

应用

Anti-Haptoglobin antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Haptoglobin (abbreviated as Hp) is the protein encoded by the HP gene in humans. It is an "acute phase" protein that has different functions displaying genetic polymorphism and has are 3 major phenotypes. Haptoglobin is capable of binding haemoglobin, there by preventing iron loss and renal damage. The complex of haptoglobin with haemoglobin is metabolized in the heptic reticuloendothelial system and it occurs in the liver, adipose tissue and in lung. It acts as an antioxidant and has antibacterial activity. Haptoglobin plays an important role in modulating many aspects of the acute phase response.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

新产品

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分析证书(COA)

Lot/Batch Number

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访问文档库

Takumi Konno et al.
Biochemical and biophysical research communications, 638, 127-133 (2022-11-30)
Zonulin is a physiologic epithelial and endothelial permeability modulator. Zonulin increases antigen trafficking from the gut lumen into the bloodstream and in between body compartments, a mechanism linked to many chronic inflammatory diseases. Upon its initial discovery, it was noted
J Wassell
Clinical laboratory, 46(11-12), 547-552 (2000-12-08)
Haptoglobin is an acute phase protein capable of binding haemoglobin, thus preventing iron loss and renal damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. There
W Dobryszycka
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 35(9), 647-654 (1997-11-14)
Haptoglobin, an "acute phase" protein, has different functions, which display genetic polymorphism. The complex of haptoglobin with haemoglobin is metabolized in the heptic reticuloendothelial system. Biosynthesis of haptoglobin occurs not only in the liver, but also in adipose tissue and
Enid E Martinez et al.
Scientific reports, 11(1), 22462-22462 (2021-11-19)
We examined the relationship between zonulin and gastric motility in critical care patients and a translational mouse model of systemic inflammation. Gastric motility and haptoglobin (HP) 2 isoform quantification, proxy for zonulin, were examined in patients. Inflammation was triggered by

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