生物来源
chicken
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
种属反应性
human
制造商/商品名称
Genway 15-288-20030F
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... B2M(567)
应用
Anti-β-2-Microglobulin antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200.
生化/生理作用
β-2-Microglobulin is a serum protein that forms a non-covalent association with the heavy chain of the major histocompatibility complex (MHC) class I, which is involved in the presentation of peptide antigens to the immune system. Defects in this gene can cause hypercatabolic hypoproteinemia. Amyloidosis is caused upon polymerization of intact β 2-microglobulin in patients on chronic hemodialysis.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
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WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
P D Gorevic et al.
Proceedings of the National Academy of Sciences of the United States of America, 83(20), 7908-7912 (1986-10-01)
Systemic amyloidosis with a predilection for bone and synovium may complicate the course of patients on long-term hemodialysis. This form of amyloidosis can be typed as distinct from other amyloid diseases by using small tissue samples obtained by bone biopsy
C Bernabeu et al.
Nature, 308(5960), 642-645 (1984-04-12)
Beta 2-microglobulin (beta 2-m) is a highly conserved polypeptide (12,000 molecular weight; 12K) noncovalently associated with the heavy chain (45-48K) of the major histocompatibility complex (MHC) class I antigens. Its synthesis is required for expression of the HLA-A/B and H-2K/D
Manzoor A Wani et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(13), 5084-5089 (2006-03-22)
Two siblings, products of a consanguineous marriage, were markedly deficient in both albumin and IgG because of rapid degradation of these proteins, suggesting a lack of the neonatal Fc receptor, FcRn. FcRn is a heterodimeric receptor composed of a nonclassical
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