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表单
solid
特点
wetted part: no
包装
pack of 100 g
制造商/商品名称
Cytiva RPN6301
颜色
White
pH值范围
5-7
溶解性
cold water: soluble (Soluble in cold water and hot water)
diethyl ether: soluble (Partially soluble in diethyl ether)
methanol: soluble (Easily soluble in methanol)
一般描述
Thiourea is a chaotrope used together with urea in the IPG strip rehydration to solubilize and denature proteins, and improve the solubility of membrane proteins.
应用
Thiourea has been used as a component of lysis buffer for solubilization of the proteins from tissue samples and T-leukemia cells. It has also been used as a component of sample buffer for placental tissue, leaf proteome, and 2D electrophoresis.
生化/生理作用
Thiourea is an organic compound and its derivatives have antibacterial, antiviral, antifungal and insecticidal property. It is actively used in the drug development against human immunodeficiency virus (HIV) and hepatitis C infection. Thiourea inhibits cyclooxygenase enzyme and effectively reduces prostaglandin E2 (PGE2) and thromboxane (TXB2) production and is antithrombotic in human platelets. It is cytotoxic to vaginal epithelial cells and may function as potent spermicidal agent. Thiourea based derivatives of anticancer drug sorafenib, eliclits antiproliferative activity in human colon cancer cell line, HCT116 cells.
储存及稳定性
Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
分析说明
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
警示用语：
Warning
储存分类代码
13 - Non Combustible Solids
法规信息
新产品
Synthesis and antiplatelet activity of antithrombotic thiourea compounds: biological and structure-activity relationship studies
Lourencco A, et al.
Molecules (Basel), 20(4), 7174-7200 (2015)
Novel thiourea compounds as dual-function microbicides
D?Cruz, OJ, et al.
Biology of Reproduction, 63(1), 196-205 (2000)
Synthesis, Characterization, Biological Activity and Use of Thiourea Derivative (PhTTU) Studies of dinitrate-1-phenyl-3-(thiazol-2-yl)-2-thioureato Cd (II) ion Complex
Alfallous KA and Aburzeza MM
International Journal of Scientific Research, 4(6) (2015)
Proteomic analysis revealed association of aberrant ROS signaling with suberoylanilide hydroxamic acid-induced autophagy in Jurkat T-leukemia cells
Li J, et al.
Autophagy, 6(6), 711-724 (2010)
Isolation and Identification of Proteins From Potato Leaves
Szajko K
Plant Breeding, 75(1), 29-36 (2017)
商品
This page describes components of rehydration solutions for use in 2-D Electrophoresis with Cytiva products.
实验方案
This page describes typical rehydration solutions for use in gel electrophoresis with Cytiva products.
This page describes two-dimensional separation of protein samples with Cytiva products.
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