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ligand
recombinant protein L (E. coli), mammalian free
包装
pack of 1 mL
制造商/商品名称
Cytiva 29-0486-65
存货情况
not available in North America
储存条件
(20% Ehtanol)
参数
5 bar
色谱柱内径
7 mm
基质
rigid, highly cross-linked agarose
平均零件尺寸
85 μm (d₅₀v is the median particle size of the cumulative volume distribution)
工作范围
2-10(pH interval where the medium can be operated without significant change in function.)
适用性
suitable for bioprocess medium
储存温度
2-8°C
一般描述
HiTrap™ Protein L columns are prepacked with Capto™ L affinity chromatography resin for purification of antibody fragments containing the kappa light chain. This resin combines a rigid, high-flow agarose matrix with the immunoglobulin-binding recombinant protein L ligand, which has a strong affinity to the variable region of antibody kappa light chains.
应用
Affinity chromatoghraphy; capture of antibodies and antibody fragments such as Fab fragments, scFv, and Dabs.
特点和优势
- Suitable for the capture of a wide range of antibody fragments such as antigen-binding fragments (Fabs), domain antibodies (dAbs), and single-chain variable fragments (scFvs).
- Enables a platform approach to antibody fragment purification.
- High binding capacity, low ligand leakage, and selectivity for a broad range of antibody fragments reduces process time and amount of resin.
- Convenient for process development, as well as small-scale purification.
- HiTrap™ format enables easy connection to a syringe, peristaltic pump, or chromatography system such as an ÄKTA™ system.
储存及稳定性
Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
法律信息
HisTrap is a trademark of Cytiva
警示用语：
Warning
危险声明
储存分类代码
3 - Flammable liquids
法规信息
新产品
Philipp A Kronenberg et al.
Frontiers in cellular and infection microbiology, 13, 1162530-1162530 (2023-04-04)
Alveolar (AE) and cystic echinococcosis (CE) are severe parasitic zoonoses caused by the larval stages of Echinococcus multilocularis and E. granulosus sensu lato, respectively. A panel of 7 monoclonal antibodies (mAbs) was selected against major diagnostic epitopes of both species.
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