ligand
N-benzyl-N-methyl ethanolamine
description
Ion Exchanger Type (value)
packaging
pkg of 1 ea
manufacturer/tradename
Cytiva 28-9269-81
parameter
44 psi
bed size
7.7 mm × 100 mm
bed volume
4.7 mL
column I.D.
7.7 mm
matrix
highly cross-linked agarose
avg. part. size
75 (d₅₀v is the median particle size of the cumulative volume distribution)
cleaning
2-14(pH interval where the medium can be subjected to, for cleaning- or sanitization-in-place.)
working range
3-12(pH interval where the medium can be operated without significant change in function.)
suitability
suitable for bioprocess medium
General description
HiScreen Capto adhere columns are prepacked with Capto adhere ion exchange chromatography resins, and are part of the process development platform available from Cytiva. The columns are an excellent choice for method optimization and parameter screening. The small column volume of 4.7 mL and bed height of 10 cm make HiScreen columns excellent tools for method optimization, parameter screening, robustness testing, and convenient scale-up. Process fluid velocities can be applied, since the 10 cm bed height gives enough residence time and the results can then serve as basis for linear process scale-up.
Features and Benefits
- Capto adhere is a multimodal anion exchanger for intermediate purification and polishing of monoclonal antibodies after the protein A capture step, giving the possibility to design a two-step chromatographic downstream process.
- Prepacked, ready-to-use columns for convenient process development optimization.
- 10 cm bed height of HiScreen columns is designed to allow method optimization and parameter screening.
- Easily connected in series to achieve 20 cm bed height.
- Small bed volume gives fast results and minimal sample/buffer consumption.
- Reproducible results, scalable to BioProcess columns packed with the same resin using the same linear fluid velocity.
Preparation Note
Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 2 to 8 °C (20% Ethanol)
Analysis Note
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
Legal Information
Capto is a trademark of Cytiva
HiScreen is a trademark of Cytiva
signalword
Warning
hcodes
存储类别
3 - Flammable liquids
法规信息
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