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安全信息

GE28-9269-73

HiScreen™ MabSelect™

Cytiva 28-9269-73

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UNSPSC代码:
13111000
NACRES:
NA.56

ligand

recombinant protein A (E. coli)

保质期

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

包装

pkg of 1 ea

制造商/商品名称

Cytiva 28-9269-73

储存条件

(20% Ehtanol)
 (20% Ethanol)

参数

44 psi

柱床尺寸

7.7 mm × 100 mm

柱床体积

4.7 mL

色谱柱内径

7.7 mm

基质

highly cross-linked agarose

平均零件尺寸

85 μm (d₅₀v is the median particle size of the cumulative volume distribution)

cleaning

2-12(pH below 3 is sometimes required to elute strongly bound IgG species. However, protein ligands may hydrolyze at very low pH.)

working range

3-10

容量

≥30 mg binding capacity (humanlgG/ml at 2.4 min residence time)(Determined at 10% breakthrough by frontal analysis at a mobile phase velocity of 500 cm/h in a column with a bed height of 20 cm.)

适用性

suitable for bioprocess medium

储存温度

2-8°C

相关类别

一般描述

HiScreen™ MabSelect™ is prepacked with MabSelect™ and is part of the process development platform available from Cytiva. The columns are an excellent choice for method optimization and parameter screening for capture of monoclonal antibodies (MAbs).

应用

The small column volume of 4.7 mL and bed height of 10 cm make HiScreen™ columns excellent tools for method optimization, parameter screening, robustness testing, and convenient scale-up. Process fluid velocities can be applied, since the 10 cm bed height gives enough residence time and the results can then serve as basis for linear process scale-up.

If necessary, two columns can easily be connected in series to give a bed height of 20 cm.

Media prepacked in HiScreen™ MabSelect™ columns are also available in other formats and as bulk packs, which makes it possible to use the same media for development work, pilot studies, and routine production.

特点和优势

  • MabSelect™ is a BioProcess medium for capture of MAbs from large sample volumes.
  • Prepacked, ready-to-use columns for convenient process development.
  • 10 cm bed height of HiScreen™ columns is designed to allow method optimization and parameter screening.
  • Easily connected in series to achieve 20 cm bed height.
  • Small bed volume gives fast results and minimal sample/buffer consumption.
  • Reproducible results, scalable to BioProcess columns packed with the same chromatography media using the same linear fluid velocity.

分析说明

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

法律信息

HiScreen is a trademark of Cytiva
MabSelect is a trademark of Cytiva

象形图

Flame
GHS02

警示用语：

Warning

危险声明

H226

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