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ligand
N-benzyl-N-methyl ethanolamine
描述
Ion Exchanger Type (value)
包装
pack of 5 × 5 mL
制造商/商品名称
Cytiva 28-4058-46
参数
<20 mL/min flow rate
42 psi
柱床尺寸
16 mm × 25 mm
柱床体积
5 mL
色谱柱内径
16 mm
基质
highly cross-linked agarose
平均零件尺寸
75 (d₅₀v is the median particle size of the cumulative volume distribution)
cleaning
2-14(pH interval where the medium can be subjected to, for cleaning- or sanitization-in-place.)
工作范围
3-12(pH interval where the medium can be operated without significant change in function.)
适用性
suitable for bioprocess medium
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一般描述
HiTrap Capto adhere is prepacked with Capto adhere, a multimodal BioProcess ion exchange resin designed to remove contaminats in post-protein A purification. Capto adhere is a strong anion exchanger with multimodal functionality. The multimodal functionality gives a different selectivity compared to traditional anion exchangers. Capto adhere is designed for post-protein A purification of monoclonal antibodies. Removal of leached protein A, aggregates, host cell proteins, nucleic acids, and viruses from monoclonal antibodies is performed in flowthrough mode at which the antibodies pass directly through the column while the contaminants are adsorbed. For optimal performance of Capto adhere, screening/optimization of loading conditions are required.
应用
Protein polishing using Capto™ Adhere Multimodal chromatography
特点和优势
- High capacity and productivity in flowthrough mode.
- Savings in time and operating costs with a two-step chromatographic process.
- Wide operational window of pH and conductivity.
- Prepacked HiTrap columns for easy screening and convenient process development.
储存及稳定性
Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (20% Ethanol)
分析说明
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
其他说明
The pressure over the packed bed varies depending on a range of parameters such as the characteristics of the chromatography medium and the column tubing used.
法律信息
Capto is a trademark of Cytiva
HiTrap is a registered trademark of Cytiva
警示用语：
Warning
危险声明
储存分类代码
3 - Flammable liquids
法规信息
新产品
实验方案
This page covers detailed information on cleaning procedures and recommended flow for column cleaning.
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