一般描述
MabSelect PrismA affinity chromatography resin has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein A-derived ligand. This allows future demands in mAb purification to be met, including processing of many bispecific antibodies.
The enhanced alkaline stability of MabSelect PrismA also provides opportunities for more robust mAb purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bioburden control for continuous processes, which can be exposed to days or weeks of feed harvest.
The enhanced alkaline stability of MabSelect PrismA also provides opportunities for more robust mAb purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bioburden control for continuous processes, which can be exposed to days or weeks of feed harvest.
特点和优势
- Enhanced binding capacity compared with other Protein A resins
- Excellent alkaline stability enables efficient cleaning and sanitization using 0.5–1.0 M NaOH
- Covered by a comprehensive security of supply program, including dual sources of the agarose base matrix and protein A ligand.
- The PrismA protein A ligand is also available in HiTrap® Fibro and HiScreen™ Fibro PrismA chromatography units for ultrafast purification of mAbs.
- Easily measure protein A leakage using the PrismA ELISA kit specifically designed for use with MabSelect™ PrismA resins.
法律信息
HiScreen is a trademark of Cytiva
HiTrap is a registered trademark of Cytiva
MabSelect is a trademark of Cytiva
警示用语：
Danger
危险声明
危险分类
Flam. Liq. 2
储存分类代码
3 - Flammable liquids
WGK
WGK 1
闪点(°F)
55.4 °F
闪点(°C)
13 °C
法规信息
新产品
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