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ligand
(Multimodal strong anion exchanger)
制造商/商品名称
Cytiva 17371520
基质
high-flow agarose
平均零件尺寸
40 μm (median particle size of the cumulative volume distribution)
cleaning in place
2-14
工作范围
3-12
容量
45-85 mg Mab/ml binding capacity
一般描述
The multimodal functionality of Capto adhere ImpRes gives a different selectivity compared with traditional ion exchange columns and it binds proteins at high or low ionic strength.
Contaminants such as DNA, host cell proteins (HCP), leached protein A, aggregates, and viruses are efficiently removed, making Capto adhere ImpRes an excellent choice for purification of MAbs and other biomolecules with high aggregate content.
Capto adhere ImpRes is designed to allow effective, high-resolution polishing of MAb in the second or third step of a purification scheme downstream of the protein A capture step.
Contaminants such as DNA, host cell proteins (HCP), leached protein A, aggregates, and viruses are efficiently removed, making Capto adhere ImpRes an excellent choice for purification of MAbs and other biomolecules with high aggregate content.
Capto adhere ImpRes is designed to allow effective, high-resolution polishing of MAb in the second or third step of a purification scheme downstream of the protein A capture step.
特点和优势
HiScreen Capto adhere ImpRes is a ready-to-use column pre-packed with BioProcess Capto adhere ImpRes strong anion exchange multimodal medium. The columns are an excellent choice for method optimization and parameter screening.
- High yields achieved through the high-resolution beads and selectivity of the ligand.
- Efficient removal of aggregates, viruses, and main contaminants in MAb processes.
- 10 cm bed height of HiScreen columns allows method optimization and parameter screening.
- Reproducible results, scalable to BioProcess columns packed with the same chromatography media using the same linear fluid velocity.
储存及稳定性
Store at 4 to 30 °C (20% ethanol)
分析说明
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
警示用语:
Warning
危险声明
储存分类代码
3 - Flammable liquids
法规信息
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