G9885
α1 -酸性糖蛋白 来源于人类血浆
≥99% (agarose gel electrophoresis)
别名:
AGP, 鼻类
产品名称
α1 -酸性糖蛋白 来源于人类血浆, ≥99% (agarose gel electrophoresis)
biological source
human plasma
assay
≥99% (agarose gel electrophoresis)
form
powder
technique(s)
ELISA: suitable
impurities
HIV-1/HIV-2, HCV and hepatitis B antigen, tested negative
UniProt accession no.
storage temp.
2-8°C
Quality Level
Gene Information
human ... ORM1(5004)
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Application
α人血浆中的 1-酸性糖蛋白已用于：
- 作为带负电荷的蛋白，以研究在聚电解质多层表面上的吸附过程
- 在研究中孵育涂有纯化抗血清的平板，以通过 ELISA 研究其血清浓度
- 研究不同浓度对人免疫缺陷病毒（HIV）蛋白酶抑制剂的抗病毒活性的影响
Biochem/physiol Actions
α1-酸性糖蛋白具有免疫调节作用。它能结合酸性药物（例如苯巴比妥）。
Disclaimer
仅供研究使用。本品在法国的科研应用受到监管，包括用于进口和出口活动（法国《公共卫生法典》Public Health Code Article L 1211-1 paragraph 2）。如《公共卫生法典》所述，购买者（即最终用户）需要从法国研究部(France Ministry of Research)获得进口授权。订购此产品即代表您已确认获得合法的进口授权。
General description
α-1-酸性糖蛋白（AGP）/血清类粘蛋白（ORM），一种糖蛋白，分子量为 41-43kDa。它被认为是人和大鼠中重要的急性期蛋白之一。AGP 可能属于脂质运载蛋白家族。
Preparation Note
从科恩级分 VI 纯化
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
Hendrik Grootaert et al.
Glycobiology, 30(9), 735-745 (2020-03-10)
The deoxy sugar l-fucose is frequently found as a glycan constituent on and outside living cells, and in mammals it is involved in a wide range of biological processes including leukocyte trafficking, histo-blood group antigenicity and antibody effector functions. The
In Vitro Effect of alpha1-Acid Glycoprotein on the Anti?Human Immunodeficiency Virus (HIV) Activity of the Protease Inhibitor CGP 61755: A Comparative Study with Other Relevant HIV Protease Inhibitors
Lazdins J K, et al.
The Journal of Infectious Diseases, 175(5), 1063-1070 (1997)
Chenhua Zhang et al.
Analytica chimica acta, 1078, 189-199 (2019-07-31)
Silica-based lectin microcolumns were developed and optimized for the separation and analysis of glycoform fractions in alpha1-acid glycoprotein (AGP) based on both the degree of branching and level of fucosylation. Concanavalin A (Con A) and Aleuria Aurantia lectin (AAL) were
Jae Woong Choi et al.
Journal of microbiology and biotechnology, 30(9), 1297-1304 (2020-07-07)
Elevated serum levels of alpha-1-acid glycoprotein (AGP) are known to be associated with several types of cancer. In addition, some reports have indicated that changes in glycosylation of AGP are associated with cancer progression. However, changes in AGP levels of
Effect of once weekly administration of mifepristone on ovarian function in normal women
Chen X and Xiao B
Contraception, 56(3), 175-180 (1997)
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