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Merck
CN

G9885

α1 -酸性糖蛋白 来源于人类血浆

≥99% (agarose gel electrophoresis)

别名:

AGP, 鼻类

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关于此项目

化学文摘社编号:
MDL number:
NACRES:
NA.32
UNSPSC Code:
12352202
Form:
powder
Assay:
≥99% (agarose gel electrophoresis)
Biological source:
human plasma
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biological source

human plasma

Quality Level

assay

≥99% (agarose gel electrophoresis)

form

powder

technique(s)

ELISA: suitable

impurities

HIV-1/HIV-2, HCV and hepatitis B antigen, tested negative

UniProt accession no.

storage temp.

2-8°C

Gene Information

human ... ORM1(5004)

General description

α-1-酸性糖蛋白(AGP)/血清类粘蛋白(ORM),一种糖蛋白,分子量为 41-43kDa。它被认为是人和大鼠中重要的急性期蛋白之一。AGP 可能属于脂质运载蛋白家族。

Application

α人血浆中的 1-酸性糖蛋白已用于:
  • 作为带负电荷的蛋白,以研究在聚电解质多层表面上的吸附过程
  • 在研究中孵育涂有纯化抗血清的平板,以通过 ELISA 研究其血清浓度
  • 研究不同浓度对人免疫缺陷病毒(HIV)蛋白酶抑制剂的抗病毒活性的影响

Biochem/physiol Actions

α1-酸性糖蛋白具有免疫调节作用。它能结合酸性药物(例如苯巴比妥)。

Preparation Note

从科恩级分  VI 纯化

Disclaimer

仅供研究使用。本品在法国的科研应用受到监管,包括用于进口和出口活动(法国《公共卫生法典》Public Health Code Article L 1211-1 paragraph 2)。如《公共卫生法典》所述,购买者(即最终用户)需要从法国研究部(France Ministry of Research)获得进口授权。订购此产品即代表您已确认获得合法的进口授权。


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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相关内容

Product Information Sheet


In Vitro Effect of alpha1-Acid Glycoprotein on the Anti?Human Immunodeficiency Virus (HIV) Activity of the Protease Inhibitor CGP 61755: A Comparative Study with Other Relevant HIV Protease Inhibitors
Lazdins J K, et al.
The Journal of Infectious Diseases, 175(5), 1063-1070 (1997)
Hendrik Grootaert et al.
Glycobiology, 30(9), 735-745 (2020-03-10)
The deoxy sugar l-fucose is frequently found as a glycan constituent on and outside living cells, and in mammals it is involved in a wide range of biological processes including leukocyte trafficking, histo-blood group antigenicity and antibody effector functions. The
Jae Woong Choi et al.
Journal of microbiology and biotechnology, 30(9), 1297-1304 (2020-07-07)
Elevated serum levels of alpha-1-acid glycoprotein (AGP) are known to be associated with several types of cancer. In addition, some reports have indicated that changes in glycosylation of AGP are associated with cancer progression. However, changes in AGP levels of



全球贸易项目编号

货号GTIN
G9885-100MG04061833650844
G9885-5MG04061833262047
G9885-10MG04061833262016
G9885-250MG04061833651278
G9885-25MG04061833651315