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一般描述
α-半乳糖苷酶来自生咖啡豆，由GLA基因编码。
应用
α-半乳糖苷酶来自生咖啡豆，已用于评估抗- α-半乳糖苷酶抗体的特异性。它还被用于抑制试验，以评估1,5-二脱氧-1,5-亚氨基-d-木糖醇活性的N-胍基衍生物。
生化/生理作用
α-半乳糖苷酶来自生咖啡豆，可切割寡糖中的末端α-半乳糖。α-半乳糖苷酶缺乏是法布里病的相关病因。
单位定义
在25℃，pH 6.5条件下，一个单位每分钟可将1.0 μmole对硝基苯基α-D-半乳糖苷水解为对硝基苯酚和D-半乳糖。
外形
悬浮在3.2M（NH4）2SO4 溶液中，pH 6.0，含有BSA
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
含少量动物源组分生物产品
Structure-function relationships in alpha-galactosidase A
Garman SC
Acta Paediatrica (Oslo, Norway : 1992), 96, 6-16 (2007)
Pig xenogeneic antigen modification with green coffee bean alpha-galactosidase
Luo Y, et al.
Xenotransplantation, 6(4), 238-248 (1999)
Orthoester functionalized N-guanidino derivatives of 1, 5-dideoxy-1, 5-imino-d-xylitol as pH-responsive inhibitors of beta-glucocerebrosidase
Sevvsek A, et al.
MedChemComm, 8(11), 2050-2054 (2017)
Eva Iniguez et al.
PLoS neglected tropical diseases, 11(10), e0006039-e0006039 (2017-10-27)
Protozoan parasites from the genus Leishmania cause broad clinical manifestations known as leishmaniases, which affect millions of people worldwide. Cutaneous leishmaniasis (CL), caused by L. major, is one the most common forms of the disease in the Old World. There
N-Guanidino Derivatives of 1, 5-Dideoxy-1, 5-imino-d-xylitol are Potent, Selective, and Stable Inhibitors of beta-Glucocerebrosidase
Sevvsek A, et al.
ChemMedChem, 12(7), 483-486 (2017)
商品
以硫酸铵悬浮液形式提供的酶的使用指南
Instructions for working with enzymes supplied as ammonium sulfate suspensions
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