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生物来源
Porcine heart
质量水平
形式
lyophilized powder
比活
≥75 units/mg protein
组成
Protein, 75-95%
储存条件
(Tightly closed. Dry. Keep locked up or in an area accessible only to qualified or authorized
persons)
技术
cell culture | mammalian: suitable
颜色
light yellow to yellow
异质活性
L-glutamic dehydrogenase, lactic dehydrogenase and malic dehydrogenase ≤0.01%
glutamic-oxalacetic transaminase ≤0.1%
储存温度
−20°C
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一般描述
谷丙转氨酶（GPT）主要分布于肝脏。
研究领域：细胞信号传导
研究领域：细胞信号传导
应用
猪心谷丙转氨酶已用于：
- 检测其对人工合成的3-甲基-2-酮戊二酸外消旋混合物进行转氨反应的能力
- 去除人胚肾细胞(HEK293)培养基中的谷氨酸
- 研究乳酸脱氢酶(LD)-丙氨酸转氨酶(ALT)酶偶联反应系统的动力学
生化/生理作用
谷丙转氨酶（GPT）介导氨基从 l-丙氨酸转移到 α-酮戊二酸，从而产生丙酮酸和谷氨酸。因此，GPT 在糖异生和氨基酸代谢中发挥着关键作用。报道显示多种肿瘤中都有GPT参与。
谷丙转氨酶 (GPT) 存在于体内大多数细胞中，但在肝脏中浓度最高。由于在肝细胞坏死后 GPT 释放入血液，可作为肝脏疾病的标志物。
单位定义
一个单位在-37°C、pH 7.6且L-丙氨酸存在条件下将 1.0μmol 酮戊二酸转化成 L -谷氨酸。
外形
含柠檬酸盐和醋酸盐的冻干粉
储存及稳定性
Tightly closed. Dry. Keep locked up or in an area accessible only to qualified or authorized
persons
persons
分析说明
双缩脲法测定蛋白质
警示用语：
Danger
危险声明
预防措施声明
危险分类
Resp. Sens. 1
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
动植物源性产品
A Comprehensive Guide to Toxicology in Nonclinical Drug Development
Faqi A S
Biomarkers journal., 2017 null
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Royal Society of Chemistry Advances, 5, 103557-103562 (2015)
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