G6761
甘氨酸 钠盐 水合物
synthetic (organic), ≥99% (HPLC), immune function, metabolism, growth and development regulator, powder
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关于此项目
线性分子式:
H2NCH2CO2Na · xH2O
化学文摘社编号:
分子量:
97.05 (anhydrous basis)
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
甘氨酸 钠盐 水合物, ≥99% (HPLC)
form
powder
mol wt
97.05 g/mol (anhydrous basis)
SMILES string
[Na+].[H]O[H].NCC([O-])=O
InChI
1S/C2H5NO2.Na.H2O/c3-1-2(4)5;;/h1,3H2,(H,4,5);;1H2/q;+1;/p-1
InChI key
CIJQGPVMMRXSQW-UHFFFAOYSA-M
biological source
synthetic (organic)
assay
≥99% (HPLC)
technique(s)
electrophoresis: suitable
mp
197-201 °C (lit.)
Quality Level
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相关类别
Application
Glycine sodium salt hydrate has been used as a component of buffer for homogenization of whole muscle for protein extraction and in electrophoresis buffer. It has also been used as a neurotransmitter in immunohistochemical staining of Zebrafish spinal cord sections.
Biochem/physiol Actions
Glycine serves as a neurotransmitter in the central nervous system. It aids in increasing the quality of sleep and neurological functions. It is essential for the regulation immune function, metabolism, growth and development. Glycine modulates intracellular Ca2+ levels and cytokines production. Studies have shown that glycine treatment effectively prevents organ transplantation failure by mitigating ischemia reperfusion injury caused by cold ischemic storage. Additionally, glycine treatment also enhances graft function during transplantation. A reduction in glycine levels is observed in obesity, type 2 diabetes (T2DM), and non-alcoholic fatty liver disease (NAFLDs). Glycine is degraded to serine by glycine serine hydroxymethyltransferase 1 in cytoplasm.
General description
Research area: Neuroscience
Glycine is a simple non-essential amino acidIt is synthesized from choline, threonine and serine. It serves as a precursor for porphyrins, purines, glutathione and creatine.
Glycine is a simple non-essential amino acidIt is synthesized from choline, threonine and serine. It serves as a precursor for porphyrins, purines, glutathione and creatine.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Multifarious beneficial effect of nonessential amino acid, glycine: a review
Razak MA, et al.
Oxidative Medicine and Cellular Longevity, 2017 (2017)
Glycine Metabolism and Its Alterations in Obesity and Metabolic Diseases
Alves A, et al.
Nutrients, 11(6), 1356-1356 (2019)
Multifarious Beneficial Effect of Nonessential Amino Acid, Glycine: A Review
Razak MA, et al.
Oxidative Medicine and Cellular Longevity (2017)
Phylogenetic relationships among five marine Catfish species (Pisces: Ariidae) from Mexico
Tenorio-Colin G, et al.
Hidrobiologica, 20(3), 266-274 (2010)
Complementary expression of calcium binding proteins delineates the functional organization of the locomotor network
Berg EM, et al.
Brain Structure &Amp; Function, 223(5), 2181-2196 (2018)
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