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一般描述
甘油醛-3-磷酸脱氢酶（GAPDH）催化甘油醛-3-磷酸以转化为D-甘油酸-1,3-二磷酸，作为糖酵解途径的一部分。还发现，GAPDH在其他细胞过程中发挥作用，如转录、凋亡、氧化应激和内质网到高尔基体的迁移。
应用
GAPDH蛋白适合用作分子生物学应用的分子量标记和蛋白质标准，包括蛋白印迹和质谱测定。
生化/生理作用
甘油醛-3-磷酸脱氢酶催化甘油醛-3-磷酸转化为D-甘油酸-1，3-二磷酸，作为糖酵解途径的一部分。
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产品编号
说明
价格
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
动植物源性产品
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Craig Nicholls et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(33), 13308-13313 (2012-08-01)
Oxidative stress regulates telomere homeostasis and cellular aging by unclear mechanisms. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is a key mediator of many oxidative stress responses, involving GAPDH nuclear translocation and induction of cell death. We report here that GAPDH interacts with
Xiaopeng Wang et al.
Molecular medicine reports, 23(2) (2020-12-11)
Acute progressive hypoxic respiratory failure caused by various predisposing factors is known as acute respiratory distress syndrome (ARDS). Although penehyclidine hydrochloride (PHC), an anticholinergic drug, is widely applied in clinical practice, the specific mechanisms underlying PHC in the treatment of
Joyce Jing Yi Wong et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(28), 10735-10740 (2006-07-04)
Type I IFNs induce the expression of IFN-stimulated gene 15 (ISG15) and its conjugation to cellular targets. ISGylation is a multistep process involving IFN-inducible Ube1L, UbcH8, and a yet-to-be identified E3 ligase. Here we report the identification of an IFN-induced
A Bosch-Comas et al.
Cellular and molecular life sciences : CMLS, 63(6), 723-734 (2006-02-28)
The biological functions of the more than one hundred genes coding for deubiquitinating enzymes in the human genome remain mostly unknown. The USP25 gene, located at 21q11.2, encodes three protein isoforms produced by alternative splicing. While two of the isoforms
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