G5171
Anti-Granulocyte Colony Stimulating Factor antibody produced in goat
IgG fraction of antiserum, lyophilized powder
别名:
Anti-G-CSF
产品名称
Anti-Granulocyte Colony Stimulating Factor antibody produced in goat, IgG fraction of antiserum, lyophilized powder
biological source
goat
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human
technique(s)
neutralization: suitable
western blot: 1-2 μg/mL
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CSF3(1440)
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Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
Application
Anti-granulocyte colony stimulating factor antibody may be used for immunoblotting at a working concentration of 1-2 μg/ml. The antibody is also suitable for neutralization assays.
General description
Mature myeloid cells are derived from bone-marrow derived precursor cells by the activity of three colony stimulating factors, granulocyte/macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF) and granulocyte colony-stimulating factor (G-CSF). The expression of G-CSF is the result of activation of pathways in response to tumor necrosis factor-α, LPS and toll-like receptor ligands. The pathways that induce the effects of G-CSF are PI3K, ERK1/2 and p38. The generation of neutrophils and induction of the circulation of hematopoietic stem cells from the bone marrow are the main functions of G-CSF. There are additional activities attributed to G-CSF such as neuroprotection, immunomodulation and generation of cardiac cells and dendritic cells. Large quantities of G-CSF are secreted in a variety of myeloid and non-myeloid cancers and rheumatoid arthritis
Monoclonal anti-granulocyte colony stimulating factor recognizes human G-CSF.
Monoclonal anti-granulocyte colony stimulating factor recognizes human G-CSF.
Immunogen
purified, recombinant human granulocyte colony stimulating factor, expressed in E. coli.
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存储类别
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
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F Liu et al.
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