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Merck
CN

G4796

Sigma-Aldrich

京尼平

≥98% (HPLC), powder, insulin stimulator

别名:

(1S,2R,6S)-2-羟基-9-(羟甲基)-3-氧杂二环[4.3.0]壬-4,8-二烯-5-羧酸甲酯

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About This Item

经验公式(希尔记法):
C11H14O5
CAS号:
分子量:
226.23
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

product name

京尼平, ≥98% (HPLC), powder

质量水平

检测方案

≥98% (HPLC)

形式

powder

溶解性

DMSO: ≥25 mg/mL
H2O: insoluble

SMILES字符串

COC(=O)C1=CO[C@@H](O)C2C1CC=C2CO

InChI

1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2,5,7,9,11-12,14H,3-4H2,1H3/t7-,9-,11-/m1/s1

InChI key

AZKVWQKMDGGDSV-BCMRRPTOSA-N

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一般描述

京尼平是一种天然的交联剂,从栀子果实中提取。它可以防止脂质过氧化和一氧化氮的产生。京尼平保护海马神经元免受阿尔茨海默氏症淀粉样β蛋白的毒性。它具有抗炎和抗血管生成的作用。京尼平参与药物输送系统。

应用

京尼平已被用于:
  • 化学敏感性测定
  • 制备重组人(rh)- 多基因成釉细胞相关蛋白(ODAM)- 浸渍胶原凝胶和体外矿化试验
  • 京尼平凝胶制剂

生化/生理作用

京尼平以 UCP2 依赖性方式刺激胰岛素分泌(解偶联蛋白 2)。 京尼平是蛋白质、胶原蛋白、明胶和壳聚糖交联剂。

特点和优势

该化合物在受体分类和信号转导手册的 InsR 页面上有重点介绍。如需浏览其他手册页面,请点击此处

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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