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Merck
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主要文件

安全信息

G3902

Sigma-Aldrich

Ghrelin human

lyophilized powder

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About This Item

MDL编号:
MFCD02687544
UNSPSC代码:
12352200
NACRES:
NA.32

表单

lyophilized powder

质量水平

200

颜色

white

溶解性

1% acetic acid: 1 mg/mL

UniProt登记号

Q9UBU3

储存温度

−20°C

基因信息

human ... GHRL(51738)

Amino Acid Sequence

Gly-Ser-Ser(O-n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg

一般描述

Ghrelin is a gastric acyl-peptide or an orexigenic digestive hormone. It is synthesized by the ghrelin producing cells in the gastric oxyntic mucosa. GHRL gene is mapped to human chromosome 3p25-p26.

应用

Ghrelin human has been used to study the influence of leptin and ghrelin on secretory function of equine corpus luteum (CL) in vitro.

生化/生理作用

Endogenous ligand to the orphan growth-hormone secretagogue receptor that stimulates the release of growth hormone from the pituitary.
Ghrelin participates in cell proliferation. It plays a major role in sleep and memory. Ghrelin is also associated with depression, especially for particular endophenotypes. It promotes growth hormone (GH) release in central nervous system.

外形

Lyophilized from 0.1% aqueous TFA

其他说明

Lyophilized from 0.1% TFA in H2O

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
108K4788
096K4790
064K4956
090K4956
090K49561

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访问文档库

Ghrelin promotes human non-small cell lung cancer A549 cell proliferation through PI3K/Akt/mTOR/P70S6K and ERK signaling pathways
Zhu J, et al.
Biochemical and biophysical research communications, 498(3), 616-620 (2018)
Helicobacter pylori and corpus gastric pathology are associated with lower serum ghrelin
Mantero P, et al.
World Journal of Gastroenterology, 24(3), 397-397 (2018)
The effects of ghrelin on sleep, appetite, and memory, and its possible role in depression: A review of the literature
Morin V, et al.
Encephale (2018)
Opposing roles of leptin and ghrelin in the equine corpus luteum regulation: an in vitro study
Galvao A, et al.
Mediators of Inflammation, 2014(2) (2014)
Obesity and variants of the GHRL (ghrelin) and BCHE (butyrylcholinesterase) genes
Dantas V G L, et al.
Genetics and Molecular Biology, 34(2), 205-207 (2011)

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