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形式
lyophilized powder
质量水平
颜色
white
溶解性
1% acetic acid: 1 mg/mL
UniProt登记号
储存温度
−20°C
基因信息
human ... GHRL(51738)
Amino Acid Sequence
Gly-Ser-Ser(O-n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg
一般描述
Ghrelin is a gastric acyl-peptide or an orexigenic digestive hormone. It is synthesized by the ghrelin producing cells in the gastric oxyntic mucosa. GHRL gene is mapped to human chromosome 3p25-p26.
应用
Ghrelin human has been used to study the influence of leptin and ghrelin on secretory function of equine corpus luteum (CL) in vitro.
生化/生理作用
Ghrelin participates in cell proliferation. It plays a major role in sleep and memory. Ghrelin is also associated with depression, especially for particular endophenotypes. It promotes growth hormone (GH) release in central nervous system.
Endogenous ligand to the orphan growth-hormone secretagogue receptor that stimulates the release of growth hormone from the pituitary.
外形
Lyophilized from 0.1% aqueous TFA
其他说明
Lyophilized from 0.1% TFA in H2O
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
The effects of ghrelin on sleep, appetite, and memory, and its possible role in depression: A review of the literature
Morin V, et al.
Encephale (2018)
Ghrelin promotes human non-small cell lung cancer A549 cell proliferation through PI3K/Akt/mTOR/P70S6K and ERK signaling pathways
Zhu J, et al.
Biochemical and biophysical research communications, 498(3), 616-620 (2018)
Helicobacter pylori and corpus gastric pathology are associated with lower serum ghrelin
Mantero P, et al.
World Journal of Gastroenterology, 24(3), 397-397 (2018)
Obesity and variants of the GHRL (ghrelin) and BCHE (butyrylcholinesterase) genes
Dantas V G L, et al.
Genetics and Molecular Biology, 34(2), 205-207 (2011)
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