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Merck
CN
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主要文件

安全信息

G3902

Sigma-Aldrich

Ghrelin human

lyophilized powder

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About This Item

MDL编号:
MFCD02687544
UNSPSC代码:
12352200
NACRES:
NA.32

表单

lyophilized powder

质量水平

200

颜色

white

溶解性

1% acetic acid: 1 mg/mL

UniProt登记号

Q9UBU3

储存温度

−20°C

基因信息

human ... GHRL(51738)

Amino Acid Sequence

Gly-Ser-Ser(O-n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg

一般描述

Ghrelin is a gastric acyl-peptide or an orexigenic digestive hormone. It is synthesized by the ghrelin producing cells in the gastric oxyntic mucosa. GHRL gene is mapped to human chromosome 3p25-p26.

应用

Ghrelin human has been used to study the influence of leptin and ghrelin on secretory function of equine corpus luteum (CL) in vitro.

生化/生理作用

Ghrelin participates in cell proliferation. It plays a major role in sleep and memory. Ghrelin is also associated with depression, especially for particular endophenotypes. It promotes growth hormone (GH) release in central nervous system.
Endogenous ligand to the orphan growth-hormone secretagogue receptor that stimulates the release of growth hormone from the pituitary.

外形

Lyophilized from 0.1% aqueous TFA

其他说明

Lyophilized from 0.1% TFA in H2O

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

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分析证书(COA)

Lot/Batch Number
108K4788
096K4790
064K4956
090K4956
090K49561

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访问文档库

Ghrelin promotes human non-small cell lung cancer A549 cell proliferation through PI3K/Akt/mTOR/P70S6K and ERK signaling pathways
Zhu J, et al.
Biochemical and biophysical research communications, 498(3), 616-620 (2018)
Helicobacter pylori and corpus gastric pathology are associated with lower serum ghrelin
Mantero P, et al.
World Journal of Gastroenterology, 24(3), 397-397 (2018)
The effects of ghrelin on sleep, appetite, and memory, and its possible role in depression: A review of the literature
Morin V, et al.
Encephale (2018)
Opposing roles of leptin and ghrelin in the equine corpus luteum regulation: an in vitro study
Galvao A, et al.
Mediators of Inflammation, 2014(2) (2014)
Obesity and variants of the GHRL (ghrelin) and BCHE (butyrylcholinesterase) genes
Dantas V G L, et al.
Genetics and Molecular Biology, 34(2), 205-207 (2011)

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