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Merck
CN

G0902

人参皂甙 Rc from Panax ginseng (Korean ginseng) root

triterpenoid saponin, ≥98% (HPLC)

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关于此项目

经验公式（希尔记法）:
C53H90O22
化学文摘社编号:
11021-14-0
分子量:
1079.27
NACRES:
NA.25
PubChem Substance ID:
24895029
UNSPSC Code:
12352201
EC Number:
234-253-5
MDL number:
MFCD00133368

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产品名称

人参皂甙 Rc from Panax ginseng (Korean ginseng) root, triterpenoid saponin, ≥98% (HPLC)

InChI key

JDCPEKQWFDWQLI-UHFFFAOYSA-N

InChI

1S/C53H90O22/c1-23(2)10-9-14-53(8,75-47-43(67)39(63)37(61)29(72-47)22-68-45-41(65)36(60)28(21-56)69-45)24-11-16-52(7)33(24)25(57)18-31-50(5)15-13-32(49(3,4)30(50)12-17-51(31,52)6)73-48-44(40(64)35(59)27(20-55)71-48)74-46-42(66)38(62)34(58)26(19-54)70-46/h10,24-48,54-67H,9,11-22H2,1-8H3

SMILES string

C\C(C)=C\CCC(C)(OC1OC(COC2OC(CO)C(O)C2O)C(O)C(O)C1O)C3CCC4(C)C3C(O)CC5C6(C)CCC(OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(C)(C)C6CCC45C

biological source

plant root (Panax ginseng)

assay

≥98% (HPLC)

form

powder

technique(s)

HPLC: suitable

storage temp.

2-8°C

Quality Level

200

相关类别

Biochem/physiol Actions

人参中发现三萜皂苷。
人参皂苷-Rc对人乳腺癌细胞系具有抗增殖作用，并可诱导亮氨酸拉链转录因子c-fos的表达。

Other Notes

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000455817
0000455817
0000321052
0000294750
0000321052

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Young Joo Lee et al.
Archives of pharmacal research, 26(1), 53-57 (2003-02-06)
We have found that ginsenoside Rc and Re induce c-fos in MCF-7 human breast carcinoma cells at both the mRNA and protein levels. However, neither ginsenoside activated the expression of reporter gene under the control of AP-1/TPA response elements. We
T B Ng et al.
Journal of ethnopharmacology, 16(2-3), 191-199 (1986-06-01)
Ginsenosides Rb2, Rc and Rg1 suppressed corticotropin-induced, dibutyryl cyclic AMP-induced and epinephrine-induced lipolysis with the relative potencies Rb2 greater than Rc greater than Rg1. The inhibition of corticotropin-induced lipolysis by ginsenoside Rg1 could not be overcome by increasing the dose
Louis Y Chan et al.
Reproductive toxicology (Elmsford, N.Y.), 19(1), 131-134 (2004-09-01)
Pregnant women commonly consume ginseng. However, there is little data concerning the effects of ginseng on early pregnancy. Rat embryos were exposed in vitro to different concentrations of Rc and Re from day 9.5 to day 11.5 after conception. Embryos
Ron Luchtefeld et al.
Journal of agricultural and food chemistry, 52(16), 4953-4956 (2004-08-05)
A method based on high-performance liquid chromatography (HPLC) and negative ion electrospray mass spectrometry (LC-MS) has been used to determine ginsenosides Rb1, Rc, and Re in six different samples of ginseng. These included a liquid extract, capsules, tea bags, and
H S Kim et al.
Neurochemical research, 25(8), 1149-1154 (2000-10-31)
We investigated the influence of centrally administered ginsenoside on the regulation of mRNA levels of the family of NMDA receptor subtypes (NR1, NR2A, NR2B, NR2C) by in situ hybridization histochemistry in the rat brain. The ginsenosides Rc and Rg1, the
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