FSL-GB3

All FSL constructs disperse in biocompatible media and spontaneously and stably incorporate into cell membranes. Cells modified with KODE constructs are known as kodecytes and usually maintain their normal vitality and functionality.

FSL-GB3 has been specifically designed to create live cells (kodecytes) expressing GB3 antigens but can also be used to modify other hydrophobic surfaces including fixed cells, virions, and solid phase surfaces. This product has been used in vitro to inhibit HIV virions and bind to veratoxin.

All FSL constructs disperse in biocompatible media and spontaneously and stably incorporate into cell membranes. FSL-GB3 has been specifically designed to create live cells (kodecytes) expressing GB3 antigens but can also be used to modify other hydrophobic surfaces including fixed cells, virions, and solid phase surfaces.

FSL-GB3 is a KODE^™ technology construct designed to label hydrophobic surfaces including living cells with blood group GB3 trisaccharide (also known as Pk). All KODE FSL constructs consist of three essential designable features: a functional component (F), a spacer (S), and a diacyl lipid (L). FSL-GB3 is comprised of the blood group GB3 (Pk) trisaccharide Galα4Galβ4Glcβ representing F, conjugated via an O(CH₂)₃NH spacer (SA1) to an activated adipate derivative of dioleoyl­phos­pha­tidyl­ethanolamine (L1).

KODE Constructs are supplied by KODE Biotech Materials Limited under license from KODE Biotech Limited.

KODE is a trademark of KODE Biotech Ltd.