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生物来源
algae (Undaria pinnatifida)
质量水平
检测方案
≥95%
形式
powder
颜色
white to off-white
有效pH范围
3.0 -7.0
溶解性
water: 10 mg/mL, clear to slightly hazy, colorless to faintly yellow
储存温度
room temp
一般描述
岩藻依丹具有复杂的化学组成。它包含甘露糖、半乳糖、葡萄糖、木糖和其他单糖。它还由糖醛酸、乙酰基和蛋白质组成。
褐藻糖胶是一种富含岩藻糖的硫酸多糖，从几种棕色海藻分离而来。
应用
裙带菜岩藻聚糖硫酸酯已被用于评估其体外抗菌潜力。
生化/生理作用
对岩藻聚糖硫酸酯的研究发现其具有广泛的生物活性 ，包括抗肿瘤和抗血管生成活性、 免疫调节、 抗炎、 抗凝血、抗血栓和抗氧化活性 。岩藻聚糖硫酸酯诱导巨噬细胞活化，随后活化有丝分裂原活化蛋白激酶 (MAPKs) 并导致自然杀伤细胞增殖。岩藻聚糖硫酸酯作为一种非选择性选择素阻断剂 ，并已被证明可诱导细胞凋亡 和抑制血管生成。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Fucoidan: structure and bioactivity
Li B, et al.
Molecules (Basel), 13(8), 1671-1695 (2008)
Arumugam Ponnan et al.
Environmental science and pollution research international, 27(25), 31760-31766 (2020-06-07)
Fucoidan is a unique bioactive and dietary polymer enriched mainly in the cell wall matrix of the brown seaweeds. This present study was intended to reveal the antigenotoxicity effect of fucoidan on 4-nitroquinolin-1-oxide (4-NQO) induced genetics damage and apoptosis in
Xiang Li et al.
Arteriosclerosis, thrombosis, and vascular biology, 34(8), 1661-1667 (2014-06-07)
Nuclear imaging of active plaques still remains challenging. Advanced atherosclerotic plaques have a strong expression of P-selectin by the endothelium overlying active atherosclerotic plaques, but not on the endothelium overlying inactive fibrous plaques. We proposed a new approach for noninvasive
Anna Pielesz et al.
The Analyst, 140(13), 4599-4607 (2015-06-02)
Differential scanning calorimetry (DSC) and thermogravimetric (TGA) investigations, acetate electrophoresis (CAE), Fourier-transform infrared spectrometry (FTIR), scanning electron microscopy (SEM) analysis and microbiological procedures were all carried out after heating the samples to a temperature sufficient for simulating a burn incident.
Wentong Cui et al.
Laboratory investigation; a journal of technical methods and pathology, 94(4), 382-393 (2014-03-13)
Endothelial dysfunction, characterized by impairment of endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) bioavailability, has been implicated in diabetic cardiovascular pathogenesis. In this study, low-molecular-weight fucoidan (LMWF), which has multiple biological activities including anti-inflammatory and anti-oxidative properties, was
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