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Merck
CN

F8190

褐藻糖胶 来源于墨角藻

≥95%

别名:

褐藻糖胶

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化学文摘社编号:
UNSPSC Code:
12352201
NACRES:
NA.25
MDL number:
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产品名称

褐藻糖胶 来源于墨角藻, ≥95%

biological source

algae (Fucus Vesiculosus)

assay

≥95%

form

powder

color

light yellow

useful pH range

5.0-11.0

solubility

water: 10 mg/mL, clear, colorless to faintly yellow

storage temp.

room temp

Quality Level

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Application

来自墨角藻的褐藻糖胶被用于:
  • 研究肝素红在检测褐藻糖胶中的应用
  • 研究其作为抗菌剂的生物活性
  • 研究其对晚期糖基化终产物的影响

Biochem/physiol Actions

对褐藻糖胶的研究发现它具有广泛的生物活性,包括抗肿瘤和抗血管生成活性、免疫调节、抗炎、抗凝血、抗血栓形成和抗氧化活性。 褐藻糖胶诱导巨噬细胞活化,随后激活促分裂原活化蛋白激酶(MAPK),并导致自然杀伤细胞增殖。 褐藻糖胶作为非选择性选择素阻断剂起作用,已被证明可诱导细胞凋亡并抑制血管生成。

General description

褐藻糖胶是一种富含岩藻糖的硫酸多糖,从几种棕色海藻分离而来。

Other Notes

为了全面了解我们针对客户研究提供的各种多糖产品,建议您访问我们的碳水化合物分类页面。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jie Zhang et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 130, 110534-110534 (2020-07-28)
Doxorubicin (DOX) is well-known for its potent antitumor activity but limited by its multiple and serious adverse effects. A major adverse effect is acute cardiotoxicity; yet, its mechanism has not been elucidated. Fucoidan is a multifunctional and nontoxic polysaccharide that
Effects of scavenger receptors-1 class A stimulation on macrophage morphology and highly modified advanced glycation end product-protein phagocytosis
Shinichi H et al.
Scientific Reports, 8(1), 5901-5901 (2018)
Bioactivity of Fucoidan as an Antimicrobial Agent in a New Functional Beverage
Poveda-Castillo et al.
Becker-Shaffer's Diagnosis and Therapy of the Glaucomas (2018)
Fanlu Wang et al.
Marine drugs, 19(4) (2021-04-04)
Fucoidans, sulfated polysaccharides extracted from brown algae, are marine products with the potential to modulate bone formation and vascularization processes. The bioactivity and safety of fucoidans are highly associated with their chemical structure, which may vary with algae species and
Quantification of sulfated polysaccharides in mouse and rat plasma by the Heparin Red mix-and-read fluorescence assay
Ulrich W et al.
ARKIVOC (Gainesville, FL, United States) (2017)

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