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Merck
CN

F8190

Sigma-Aldrich

褐藻糖胶 来源于墨角藻

≥95%

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别名:
褐藻糖胶
CAS号:
MDL编号:
UNSPSC代码:
12352201
NACRES:
NA.25

生物来源

algae (Fucus Vesiculosus)

质量水平

检测方案

≥95%

形式

powder

颜色

light yellow

有效pH范围

5.0-11.0

溶解性

water: 10 mg/mL, clear, colorless to faintly yellow

储存温度

room temp

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一般描述

褐藻糖胶是一种富含岩藻糖的硫酸多糖,从几种棕色海藻分离而来。

应用

来自墨角藻的褐藻糖胶被用于:
  • 研究肝素红在检测褐藻糖胶中的应用
  • 研究其作为抗菌剂的生物活性
  • 研究其对晚期糖基化终产物的影响

生化/生理作用

对褐藻糖胶的研究发现它具有广泛的生物活性,包括抗肿瘤和抗血管生成活性、免疫调节、抗炎、抗凝血、抗血栓形成和抗氧化活性。 褐藻糖胶诱导巨噬细胞活化,随后激活促分裂原活化蛋白激酶(MAPK),并导致自然杀伤细胞增殖。 褐藻糖胶作为非选择性选择素阻断剂起作用,已被证明可诱导细胞凋亡并抑制血管生成。

其他说明

为了全面了解我们针对客户研究提供的各种多糖产品,建议您访问我们的碳水化合物分类页面。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Effects of scavenger receptors-1 class A stimulation on macrophage morphology and highly modified advanced glycation end product-protein phagocytosis
Shinichi H et al.
Scientific Reports, 8(1), 5901-5901 (2018)
Fanlu Wang et al.
Marine drugs, 19(4) (2021-04-04)
Fucoidans, sulfated polysaccharides extracted from brown algae, are marine products with the potential to modulate bone formation and vascularization processes. The bioactivity and safety of fucoidans are highly associated with their chemical structure, which may vary with algae species and
Bioactivity of Fucoidan as an Antimicrobial Agent in a New Functional Beverage
Poveda-Castillo et al.
Becker-Shaffer's Diagnosis and Therapy of the Glaucomas (2018)
Li-Mei Chen et al.
Scientific reports, 7(1), 11864-11864 (2017-09-21)
Low-molecular-weight Fucoidan (Oligo-Fucoidan) is a sulfated polysaccharide that has a variety of biological effects and has also been shown to have beneficial health effects. However, the molecular mechanisms underlying the therapeutic effects of Oligo-Fucoidan in patients with cancer remain unclear.
Jie Zhang et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 130, 110534-110534 (2020-07-28)
Doxorubicin (DOX) is well-known for its potent antitumor activity but limited by its multiple and serious adverse effects. A major adverse effect is acute cardiotoxicity; yet, its mechanism has not been elucidated. Fucoidan is a multifunctional and nontoxic polysaccharide that

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