产品名称
阳离子铁蛋白 来源于马脾脏, 10 mg/mL in 0.15 M NaCl
biological source
horse spleen
sterility
sterile-filtered
form
liquid
concentration
10 mg/mL in 0.15 M NaCl
technique(s)
cell culture | mammalian: suitable
electron microscopy: suitable
UniProt accession no.
storage temp.
2-8°C
Quality Level
Gene Information
horse ... FTL(100051593)
Application
一种阳离子衍生物,用于标记带负电荷的细胞膜,以便电镜观察。
从马脾阳离子化的铁蛋白已用于:
- 在研究中孵育阿米巴 (106),确定滋养体是否能够吸收铁蛋白并内化该蛋白,使其在无菌培养中生长
- 通过电子显微镜检查确定吞噬体-溶酶体融合
- 在无血清孵育介质中标记新鲜切除的鸡视神经盖
铁蛋白是一种铁储存蛋白,在铁代谢中发挥核心角色,在炎症或恶性疾病中可能升高。它在研究中被用作机体铁供应的指标,但在慢性炎症存在时可能被证明是不准确的。
Biochem/physiol Actions
铁蛋白将铁保持在其三价铁状态 (Fe 3 + )。铁蛋白的核心具有容纳 4500 个铁分子的能力。在脊椎动物中储存铁是必不可少的。铁蛋白在无脊椎动物中也是储存和运输铁的必需物质,并在膳食铁吸收中起关键作用。
General description
铁蛋白是一种铁贮藏蛋白,通常存在于哺乳动物的肝脏和脾脏中。铁和铁蛋白在眼内的分布基本相同。铁蛋白由重链和轻链组成。
Preparation Note
将马脾铁蛋白与 N,N-二甲基-1,3-丙二胺 (DMPA) 偶联制备。
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
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