生物来源
horse spleen
质量水平
无菌性
sterile-filtered
形式
liquid
浓度
10 mg/mL in 0.15 M NaCl
技术
cell culture | mammalian: suitable
electron microscopy: suitable
UniProt登记号
储存温度
2-8°C
基因信息
horse ... FTL(100051593)
一般描述
铁蛋白是一种铁贮藏蛋白，通常存在于哺乳动物的肝脏和脾脏中。铁和铁蛋白在眼内的分布基本相同。铁蛋白由重链和轻链组成。
应用
一种阳离子衍生物，用于标记带负电荷的细胞膜，以便电镜观察。
从马脾阳离子化的铁蛋白已用于：
- 在研究中孵育阿米巴 (106)，确定滋养体是否能够吸收铁蛋白并内化该蛋白，使其在无菌培养中生长
- 通过电子显微镜检查确定吞噬体-溶酶体融合
- 在无血清孵育介质中标记新鲜切除的鸡视神经盖
铁蛋白是一种铁储存蛋白，在铁代谢中发挥核心角色，在炎症或恶性疾病中可能升高。它在研究中被用作机体铁供应的指标，但在慢性炎症存在时可能被证明是不准确的。
生化/生理作用
铁蛋白将铁保持在其三价铁状态 (Fe 3 + )。铁蛋白的核心具有容纳 4500 个铁分子的能力。在脊椎动物中储存铁是必不可少的。铁蛋白在无脊椎动物中也是储存和运输铁的必需物质，并在膳食铁吸收中起关键作用。
制备说明
将马脾铁蛋白与 N,N-二甲基-1,3-丙二胺 (DMPA) 偶联制备。
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
动植物源性产品
Fabrizio Bardelli et al.
Scientific reports, 7, 44862-44862 (2017-03-24)
Once penetrated into the lungs of exposed people, asbestos induces an in vivo biomineralisation process that leads to the formation of a ferruginous coating embedding the fibres. The ensemble of the fibre and the coating is referred to as asbestos
Interaction of Legionella pneumophila with Acanthamoeba castellanii: uptake by coiling phagocytosis and inhibition of phagosome-lysosome fusion.
Bozue J A and Johnson W
Infection and Immunity, 64(2), 668-673 (1996)
R H Adamson et al.
The Journal of physiology, 445, 473-486 (1992-01-01)
1. We have investigated the interaction of plasma proteins with the endothelial cell using cationized ferritin as a marker of the cell surface glycocalyx. 2. Single microvessels of the frog mesentery were sequentially perfused using glass micropipettes with solutions containing
Jennifer R Charlton et al.
American journal of physiology. Renal physiology, 321(3), F293-F304 (2021-07-21)
Kidney pathologies are often highly heterogeneous. To comprehensively understand kidney structure and pathology, it is critical to develop tools to map tissue microstructure in the context of the whole, intact organ. Magnetic resonance imaging (MRI) can provide a unique, three-dimensional
Jennifer R Charlton et al.
BMC nephrology, 24(1), 178-178 (2023-06-19)
A significant barrier to biomarker development in the field of acute kidney injury (AKI) is the use of kidney function to identify candidates. Progress in imaging technology makes it possible to detect early structural changes prior to a decline in
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门