推荐产品
生物来源
human spleen
质量水平
无菌性
sterile-filtered
类型
Type V
表单
liquid
包装
vial of 2 μg
浓度
10 μg/mL in 0.15 M NaCl, 10 mM Tris, pH 8.0, containing 0.1% sodium azide
储存温度
2-8°C
基因信息
human ... FTH1(2495) , FTL(2512)
应用
Ferritin is an iron storage protein that plays a central role in iron metabolism, and may be elevated in inflammatory or malignant diseases. It has been used in studies as an indicator of body iron supply, but may prove inaccurate in in the presence of chronic inflammation.
生化/生理作用
A ubiquitous iron storage protein that plays a key role in iron metabolism. It serves as an intracellular iron reserve (particularly in spleen, liver, intestinal mucosa, and bone marrow) and functions in iron detoxification. Studies have shown that ferritin iron incorporation is mediated by a ferroxidase activity associated with ferritin H subunits and a nucleation center associated with ferritin L subunits. Release of iron from ferritin has an essential role in iron-dependent lipid peroxidation and may contribute to free radical-induced cell damage in vivo. Therefore, by binding iron, ferritin may function as an antioxidant.
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Samir Awadallah et al.
Clinical laboratory, 59(5-6), 687-691 (2013-07-20)
Total antioxidant capacity (TAC) and ischemia modified albumin (IMA) are common parameters used to assess the status of oxidative stress under different conditions. This study reports on TAC and levels of IMA in patients with beta-thalassemia major. Blood specimens were
Edward Pelle et al.
Journal of cosmetic science, 64(3), 175-179 (2013-06-12)
Menstruation and desquamation are important routes for humans to excrete iron. Because menstruation is no longer available in postmenopausal women, in the present study, we examined whether iron accumulates more in postmenopausal skin than in premenopausal skin. Skin biopsy samples
Flavia G N Rosado et al.
American journal of clinical pathology, 139(6), 713-727 (2013-05-22)
Hemophagocytic lymphohistiocytosis (HLH) is a frequently fatal and likely underdiagnosed disease involving a final common pathway of hypercytokinemia, which can result in end-organ damage and death. Although an early diagnosis is crucial to decrease mortality, the definitive diagnosis is often
Rachel Collings et al.
The American journal of clinical nutrition, 98(1), 65-81 (2013-05-31)
Absorption factors are required to convert physiologic requirements for iron into Dietary Reference Values, but the absorption from single meals cannot be used to estimate dietary iron absorption. The objective was to conduct a systematic review of iron absorption from
Ann Kruger et al.
Nephrology nursing journal : journal of the American Nephrology Nurses' Association, 40(2), 135-139 (2013-06-19)
This study examined whether a change infrequency of administration of erythropoietin-stimulating agent affected hemoglobin levels in patients on peritoneal dialysis. Data were extracted from the Australian Renal Anaemia Management database for the years 2002 and 2008. Less frequent dosing and
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