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生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
lyophilized powder
种属反应性
horse
技术
immunoelectrophoresis: suitable
immunoelectrophoresis: suitable
indirect ELISA: 1:10,000
储存温度
2-8°C
靶向翻译后修饰
unmodified
基因信息
horse ... Ftl(100051593)
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一般描述
Ferritin consists of homogenous protein segment called as apoprotein and an iron segment which binds to the apoprotein. It is composed of heavy (H) and light (L) chains.
Ferritin is the storage form of iron in mammals, found mainly in liver, bone marrow and spleen. It is also present in small intestine, placenta, kidney and heart. Horse spleen ferritin is made up of 24 identical subunits. Ferritin of different organs is distinct with different electrophoretic mobility and possible functional differences.
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特异性
The antibody specifically recognizes ferritin from horse spleen.
免疫原
Purified horse spleen ferritin
应用
Anti-Horse Spleen Ferritin antibody was used for immunocytochemistry of rat brain sections at a working antibody dilution of 1:2000 and in mouse brain sections at 1:1000. The antibody was used for immunoblotting using cell lysates of mouse primary erythroblasts and human ovarian carcinoma cells and human bronchial epithelial cells at a working dilution of 1:1000. The antibody is suitable for immunoelectrophoresis.
Horse Spleen Ferritin antibody has been used:
- immunofluorescence
- in western blotting
- in immunohistochemistry
生化/生理作用
Ferritin iron is oxidized from Fe(II) to Fe(III) in the presence of the enzyme ferroxidase.
外形
Lyophilized from 0.01 M sodium phosphate, 0.015 M sodium chloride, pH 7.2
重悬
Reconstitute with 0.135 M sodium chloride.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Jan A Gorter et al.
Epilepsia, 46(9), 1371-1379 (2005-09-09)
Iron accumulation in the brain has been associated with neurodegenerative disorders, including epilepsy. In our previous SAGE study, we showed that ferritin, an iron-storage protein, was one of the genes (Ferritin-H) that showed overexpression before the chronic epileptic phase. In
New functions for an iron storage protein: the role of ferritin in immunity and autoimmunity
Recalcati S, et al.
Journal of Autoimmunity, 30(1-2), 84-89 (2008)
Microglial pathology in Down syndrome
Xue Q S and Streit W J
Acta Neuropathologica, 122(4), 455-455 (2011)
Transferrin ensures survival of ovarian carcinoma cells when apoptosis is induced by TNF$\alpha$, FasL, TRAIL, or Myc
Fassl S, et al.
Oncogene, 22(51), 8343-8343 (2003)
Jennifer R Charlton et al.
Nanomedicine : nanotechnology, biology, and medicine, 12(6), 1735-1745 (2016-04-14)
Ferritin is a naturally occurring iron storage protein, proposed as a clinically relevant nanoparticle with applications as a diagnostic and therapeutic agent. Cationic ferritin is a targeted, injectable contrast agent to measure kidney microstructure with MRI. Here, the toxicity of
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