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Merck
CN

F5022

Sigma-Aldrich

Fibronectin-like Protein Polymer genetically engineered

lyophilized powder, autoclaved, BioReagent, suitable for cell culture

别名:

ProNectin® F

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About This Item

MDL编号:
UNSPSC代码:
12352200

无菌性

autoclaved

质量水平

产品线

BioReagent

表单

lyophilized powder

分子量

75 kDa by gene sequence (differences are due to the unusual amino acid composition of the protein)
~110 kDa by SDS-PAGE

包装

pkg of 1 mg
pkg of 5 mg

技术

cell culture | mammalian: suitable

溶解性

4.5  M LiClO4: 1 mg/mL (stable for 12 mo. at RT.)

运输

dry ice

储存温度

room temp

应用

Recommended as a cell culture substratum at 2-10 μg/cm2.

包装

Supplied with diluent in separate vial.

其他说明

Positively-charged, protein polymer which incorporates multiple copies of the RGD cell attachment epitope from human fibronectin between repeated structural peptide units.

重悬

Dilutions can be made to a working concentration with balanced salt solution; stable up to 2 days at RT. Coated labware is stable at least 4 mos at RT.

法律信息

ProNectin is a registered trademark of Sanyo Chemical Industries, Ltd

象形图

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警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Ox. Liq. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

5.1B - Oxidizing hazardous materials

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Receptor-specific serum-free cell attachment using a highly stable engineered protein polymer.
Esty, A.
American Biotechnology Laboratory, 44-44 (1991)
Zoltán Jakus et al.
The Journal of experimental medicine, 206(3), 577-593 (2009-03-11)
beta(2) integrins and Fcgamma receptors are critically involved in neutrophil activation at the site of inflammation. Both receptor types trigger a receptor-proximal tyrosine phosphorylation cascade through Src family kinases and Syk, but further downstream signaling events are poorly understood. We
Polly A Machin et al.
Frontiers in immunology, 14, 1180886-1180886 (2023-06-29)
Rac-GTPases and their Rac-GEF activators play important roles in neutrophil-mediated host defence. These proteins control the adhesion molecules and cytoskeletal dynamics required for neutrophil recruitment to inflamed and infected organs, and the neutrophil effector responses that kill pathogens. Here, we
Lamyaa Shaban et al.
PLoS pathogens, 16(5), e1008576-e1008576 (2020-05-12)
Yersinia suppress neutrophil responses by using a type 3 secretion system (T3SS) to inject 6-7 Yersinia effector proteins (Yops) effectors into their cytoplasm. YopH is a tyrosine phosphatase that causes dephosphorylation of the adaptor protein SKAP2, among other targets in

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