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一般描述
2-氟-2-脱氧-D-葡萄糖无毒,是葡萄糖的结构类似物,显著抑制了糖基化。作为葡萄糖类似物,2-氟-2-脱氧-D-葡萄糖在大脑和心脏细胞中可被迅速摄取。
2-氟-2-脱氧-D-葡萄糖可以被细胞吸收,但不进行代谢性糖酵解。
2-氟-2-脱氧-D-葡萄糖可以被细胞吸收,但不进行代谢性糖酵解。
应用
2-氟-2-脱氧-D-葡萄糖被用作快速肿瘤检测的示踪剂。它被用作葡萄糖模拟物,以研究辐射和烧伤小鼠的葡萄糖摄取。肿瘤治疗研究使用FDG联合PET(正电子发射地形图)
生化/生理作用
抑制细胞糖基化的葡萄糖类似物。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
从最新的版本中选择一种:
分析证书(COA)
The American journal of clinical nutrition, 98(1), 57-64 (2013-05-31)
Studies in rodents have shown that brown adipose tissue (BAT) is activated on food intake, thereby reducing metabolic efficiency. The current study investigated whether a single high-calorie, carbohydrate-rich meal activates BAT in lean human adults. BAT activity was studied in
Cancer, 117(20), 4582-4594 (2011-03-25)
Indeterminate results at fine-needle aspiration biopsy (FNAB) of thyroid nodules pose a clinical dilemma, because only 20% to 30% of patients suffer from malignancy. Previous studies suggested that the false-negative ratio of [(18)F]-2-fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET) is very low; therefore
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(1), 99-106 (2013-11-16)
Sarcoidosis is a systemic granulomatous disease of unknown etiology. Cardiac involvement may occur, leading to an adverse outcome. Although early treatment to improve morbidity and mortality is desirable, sensitive and accurate detection of cardiac sarcoidosis remains a challenge. Accordingly, interest
Epilepsia, 54(7), 1240-1250 (2013-05-31)
Posttraumatic epilepsy (PTE) occurs in a proportion of traumatic brain injury (TBI) cases, significantly compounding the disability, and risk of injury and death for sufferers. To date, predictive biomarkers for PTE have not been identified. This study used the lateral
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 21(7), 670-675 (1980-07-01)
Rapid uptake of F-18 FDG was observed in a variety of transplanted and spontaneous tumors in animals. The tumor uptake reached a peak by 30 min and remained relatively constant up to 60 min, with a very slow wash-out of
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