推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
IgG fraction of antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
human
包装
antibody small pack of 25 μL
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1,000 using human tissue (Indirect Immunoperoxidase Labeling)
indirect immunofluorescence: 1:200 using formalin-fixed, paraffin-embedded sections of human tissue
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... VWF(7450)
一般描述
人血管性血友病因子(因子VIII R:Ag)是一种分子量270 kDa的多聚体血浆糖蛋白。血管性血友病因子具有血小板糖蛋白Ib、糖蛋白IIb/IIIa、胶原蛋白和肝素的功能结合域。这种因子是由内皮细胞合成的,也存在于血小板和巨核细胞中。
抗血管性血友病因子抗体是以纯化的血管性血友病因子(因子VIII R:Ag)为免疫原在家兔体内生产的。
特异性
抗体特异性地与来自正常和肿瘤血液以及淋巴管的人内皮细胞的细胞质反应。它还与人类心内膜、血小板和巨核细胞发生反应。它可用于冷冻组织制剂和酶促预消化、福尔马林、甲基卡那、Bouin 或乙醇固定和石蜡包埋组织切片中血管结构的免疫组织学研究。
免疫原
来自人血浆的血管性血友病因子(因子 VIII 相关抗原)。
应用
兔抗血管性血友病因子抗体可用于:
- 蛋白质印迹分析和免疫染色
- 免疫细胞化学
- 免疫组织化学
- 间接免疫荧光法
生化/生理作用
它介导了血小板在受伤血管壁上的附着,并可作为凝血因子VIII的载体和稳定剂。
外形
0.01 M 磷酸盐缓冲液(pH 7.4,含有 15 mM 叠氮化钠)溶液
制备说明
纯化完整的抗血清以提供抗血清的 IgG 部分。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
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