biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
fractionated antiserum
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human, bovine, rat
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, indirect ELISA: suitable, western blot: 1:1,000
impurities
endotoxin, tested
UniProt accession no.
application(s)
research pathology
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
bovine ... FGF2(281161)
human ... FGF2(2247)
rat ... Fgf2(54250)
General description
碱性成纤维细胞生长因子(FGFb),也称为NUDT6(nudix(核苷二磷酸连接部分X)型基序6)由定位于人染色体4q28.1的基因编码。FGFb基因跨越基因组DNA上的34271 bp,包含16个外显子和6个内含子。FGFb RNA转录物在各种人体组织中表达,包括肝脏,胸腺,脾脏,外周血白细胞,心脏骨骼肌,睾丸,结肠和肾脏。
Immunogen
对应于人牛FGF2(1-24)的合成肽序列
Application
兔源抗碱性成纤维细胞生长因子(1-24)抗体可用于:
- 免疫组化
- 免疫染色
- 免疫印迹
Biochem/physiol Actions
碱性成纤维细胞生长因子(也称为bFGF)是一种多效性细胞因子,是一种有效的促有丝分裂因子。bFGF与其同源受体酪氨酸激酶FGFR结合后,能够激活MAPK和PI3K等途径,并在多种细胞类型中产生细胞效应。据报道,碱性成纤维细胞生长因子可诱导成纤维细胞增殖,分化,伤口愈合和再生,肢体形成,组织重塑和血管生成。
Physical form
从磷酸盐缓冲生理盐水中的0.2 μm滤过溶液冻干。
Analysis Note
生物活性:抗成纤维细胞生长因子-碱性(1-24)导致FGF-碱性的促有丝分裂活性呈剂量依赖性降低,因此1:50的最终稀释度中和了1个单位FGF碱性的生物活性。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
低风险生物材料
常规特殊物品
此项目有
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| F3393-5X.1ML | 04061835807697 |
| F3393-.1ML | 04061838172686 |