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应用
Factor Xa 生色底物已被用于胎盘细胞器蛋白和约安巨马陆的factor Xa蛋白酶检测。
生化/生理作用
Factor Xa生色底物含有Bz-Ile-Glu-Gly-Arg-pNA肽序列。Factor Xa会介导底物水解后p-NA 色原体的释放，释放量可以通过光度法测定。
物理属性
人因子 Xa 的 KM 约为 0.8mM
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Probing substrate-induced conformational alterations in adrenoleukodystrophy protein by proteolysis
Guimaraes CP, et al.
Journal of Human Genetics, 50(2), 99-99 (2005)
Joannsin, a novel Kunitz-type FXa inhibitor from the venom of Prospirobolus joannsi
Luan N, et al.
Thrombosis and Haemostasis, 117(06), 1031-1039 (2017)
Pathology consultation on anticoagulation monitoring: factor X-related assays
Wool GD and Lu CM
American Journal of Clinical Pathology, 140(5), 623-634 (2013)
Zilei Duan et al.
Cellular and molecular life sciences : CMLS, 79(6), 309-309 (2022-05-22)
Blood clot formation induced by dysfunctional coagulation is a frequent complication of coronavirus disease 2019 (COVID-19) and a high-risk factor for severe illness and death. Neutrophil extracellular traps (NETs) are implicated in COVID-19-induced immunothrombosis. Furthermore, human cathelicidin, a NET component
Ning Luan et al.
Thrombosis and haemostasis, 117(6), 1031-1039 (2017-03-10)
The repugnatorial glands of millipedes release various defensive chemical secretions. Although varieties of such defensive secretions have been studied, none of them is protein or peptide. Herein, a novel factor Xa (FXa) inhibitor named joannsin was identified and characterised from repugnatorial glands
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