生物来源
bovine serum (fetal)
质量水平
形式
lyophilized powder
技术
HPLC: suitable
MALDI-MS: suitable
杂质
~0.2% free N-acetylneuraminic acid
UniProt登记号
储存温度
2-8°C
基因信息
bovine ... FETUB(504615)
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一般描述
胎球蛋白是从胎牛血清中提取的一种丰富的糖基化蛋白，具有运输和储存蛋白的功能。它也被称为α2-Heremans-Schmid糖蛋白(AHSG)，对应的分子量为64 kDa。胎球蛋白属于他汀类药物，主要在肝脏合成，部分在肾脏、胎盘和舌头合成。
应用
从胎牛血清中提取胎素已用于：
- 基质辅助激光解吸/电离-质谱(MALDI-MS)和高效液相色谱-荧光检测分析(HPLC-FLD)中的标准糖蛋白
- 作为百日咳毒素疫苗碳水化合物结合试验中的配体
- 药物载体研究的胎素-A偶联金纳米颗粒(F-GNP)的合成
生化/生理作用
在人类中，胎素基因的多态性与2型糖尿病和调节脂肪细胞功能有关。在肥胖和非酒精性脂肪肝(NAFLD)中观察到胎素水平升高。胎球蛋白是临床诊断代谢紊乱的潜在指标。
制备说明
通过凝胶过滤进一步处理F2379。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
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